Evidence map›Paper›PMID 24614203›Full record

ArticleJournal of geriatric psychiatry and neurology2014

Cognitive complaints correlate with depression rather than concurrent objective cognitive impairment in the successful aging evaluation baseline sample.

Zvinka Z Zlatar, Raeanne C Moore, Barton W Palmer, Wesley K Thompson, Dilip V Jeste

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of geriatric psychiatry and neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zvinka Z ZlatarDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, CA, USA zzlatar@ucsd.edu.
Raeanne C MooreDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, CA, USA.
Barton W PalmerDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, CA, USA.
Wesley K ThompsonDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, CA, USA.
Dilip V JesteDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, CA, USA.

Funding

SAN DIEGO CLINICAL AND TRANSLATIONAL RESEARCH INSTITUTEUL1RR031980 · NCRR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2010 to 2011
$14.0M
FELLOWSHIP IN GERIATRIC MENTAL HEALTHT32MH019934 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth W Twamley · 1994 to 2026
$9.5M
CORE--RESEARCH NETWORK DEVELOPMENT COREP30MH066248 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JESTE, DILIP V. · 2002 to 2006
$7.4M
NCRR NIH HHS UL1 RR031980NCRR NIH HHS UL1RR031980NIMH NIH HHS P30 MH066248NIMH NIH HHS P30MH066248NIMH NIH HHS T32 MH019934NIMH NIH HHS T32MH019934
6 · The paper itself

Abstract

objectiveWhether subjective cognitive complaints are suggestive of depression or concurrent cognitive impairment in older adults without dementia remains unclear. The current study examined this question in a large (N = 1000), randomly selected, community-based sample of adults aged 51 to 99 years without a formal diagnosis of dementia (Successful AGing Evaluation [SAGE] study).

methodsThe modified Telephone Interview for Cognitive Status (TICS-m) measured objective cognitive function, the Cognitive Failures Questionnaire (CFQ) measured subjective cognitive complaints, and the 9-item Patient Health Questionnaire (PHQ-9) measured depression. Spearman ρ correlations and linear regression models were conducted to examine the relationship among variables in the baseline SAGE sample.

resultsThere was a weak association between TICS-m and CFQ scores (ρ = -.12); however, a moderate to large association was observed for CFQ and PHQ-9 (ρ = .44). Scores on the CFQ were not associated with TICS-m scores (β = -.03, P = .42) after controlling for PHQ-9 and variables of interest, such as age, gender, ethnicity, and physical functioning, while PHQ-9 was significantly associated with CFQ scores (β = .46, P < .001) after controlling for variables of interest.

conclusionsSubjective cognitive complaints are more likely related to symptoms of depression rather than concurrent cognitive impairment in a large cross-section of community-dwelling adults without a formal diagnosis of dementia.

Indexed as

CognitionAgedAged, 80 and overAgingCognition DisordersCross-Sectional StudiesDepressionFemaleHumansInterview, PsychologicalMaleMiddle AgedSurveys and Questionnairesagingcognitive failures questionnaire (CFQ)cognitive functiondepressionmodified telephone interview for cognitive status (TICS-m)subjective cognitive complaints

Identifiers

PMID24614203
PMCPMC4255945

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.