ArticleScientific reports2014
Association between red blood cell transfusion and bronchopulmonary dysplasia in preterm infants.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Risk factors for bronchopulmonary dysplasia in preterm infants: a systematic review and meta-analysis.PeerJ · 2025Pooled it
- Neurodevelopmental outcomes after red cell transfusion exposure in male versus female extremely preterm infants.Pediatric research · 2025Trial
- Iron supplementation and the risk of bronchopulmonary dysplasia in extremely low gestational age newborns.Pediatric research · 2023Trial
- Improving early risk stratification for bronchopulmonary Dysplasia in preterm infants using machine learning: development and external validation.Annals of medicine · 2026Article
- Assessment of iron sufficiency in premature infants treated with darbepoetin using conventional and novel erythrocyte metrics.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Blood transfusion in pediatric sepsis-associated acute kidney injury: a nationwide study of risk factors and outcomes.Pediatric nephrology (Berlin, Germany) · 2026Article
- The relationship between erythrocyte transfusion in very preterm infants and inflammatory cytokines and morbidities: a prospective observational study.BMC pediatrics · 2026Observational
- Association of red blood cell transfusions with bronchopulmonary dysplasia in preterm infants: a retrospective cohort study.BMJ paediatrics open · 2026Article
- Three studies needed to inform the design of the U-BET (umbilical cord blood for extremely low-gestational-age transfusions) clinical trial.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- The risk of developing severe bronchopulmonary dysplasia: evaluating associations with the nucleated red blood cell count at birth and volume of transfusions received.Frontiers in pediatrics · 2026Article
- Environmental exposures in the neonatal intensive care unit impacting neurodevelopmental outcomes for neonates.Pediatric research · 2025Review
- Red blood cell transfusion frequency and the risk and severity of bronchopulmonary dysplasia in preterm infants: a retrospective cohort study.BMC pediatrics · 2025Article
- Blood Donor Sex and Outcomes in Transfused Infants.Clinics in perinatology · 2023Review
- Impact of level of neonatal care on phlebotomy and blood transfusion in extremely low birthweight infants: a prospective, multicenter, observational study.Frontiers in pediatrics · 2023Article
- Association between the development of bronchopulmonary dysplasia and platelet transfusion: a protocol for a systematic review and meta-analysis.Frontiers in pediatrics · 2023Article
- Association between red blood cell transfusion and bronchopulmonary dysplasia: a systematic review and meta-analysis.Frontiers in pediatrics · 2023Review
- Comparison of Hematocrit Change in Preterm Neonates with Birth Weight Based Versus Formula Based Packed Red Blood Cell Transfusion: A Randomized Control Trial.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2022Article
- Thresholds for blood transfusion in extremely preterm infants: A review of the latest evidence from two large clinical trials.Frontiers in pediatrics · 2022Review
- Feasibility of umbilical cord blood as a source of red blood cell transfusion in preterm infants.Blood transfusion = Trasfusione del sangue · 2021Observational
- Analysis of correlative risk factors for blood transfusion therapy for extremely low birth weight infants and extreme preterm infants.American journal of translational research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anemia and the need for transfusion of packed red blood cells (PRBCs) are common in preterm infants. PRBC transfusion increases the oxygen carrying capacity of hemoglobin and may result in higher rates of organ dysfunction. To determine whether PRBC transfusion in preterm infants is associated with an increased incidence of bronchopulmonary dysplasia (BPD), this retrospective study was performed on neonates with birth weights ≤ 1,500 g or gestational age ≤ 32 weeks admitted from August, 2008 to November, 2013. Infants who received PRBC transfusion before the diagnosis of BPD and those who did not receive PRBC transfusion or received PRBC transfusion after diagnosis of BPD were compared for incidence of BPD and other morbidities. Of 231 preterm infants, 137 received PRBC transfusion before BPD was diagnosed (group 1) and 94 did not (group 2). The incidence of BPD was significantly higher in group 1 than in group 2 (37.2% vs. 2.1%, P < 0.00001). After adjusting for potential risk factors, the adjusted odds ratio for BPD was 9.80 (95% confidence interval, 1.70-56.36; P = 0.01). This study demonstrated an association between PRBC transfusion and BPD in preterm infants. A cautious approach to PRBC transfusion in these infants is warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.