Evidence map›Paper›PMID 24614140›Full record

ReviewNature reviews. Clinical oncology2014

Diagnosis and management of lymphomas and other cancers in HIV-infected patients.

Antonino Carbone, Emanuela Vaccher, Annunziata Gloghini, Liron Pantanowitz, Akin Abayomi, Paolo de Paoli, Silvia Franceschi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Clinical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 135 citations in OpenAlex.

  1. CD20-negative diffuse large B cell lymphoma: a comprehensive analysis of 695 cases.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Pooled it
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  13. Exploration and analysis of differentially expressed genes in Epstein-Barr virus negative and positive plasmablastic lymphoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article
  14. Review
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  16. Human Immunodeficiency Virus Related Non-Hodgkin's Lymphoma.Blood and lymphatic cancer : targets and therapy · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Antonino CarboneDepartment of Pathology, Centro di Riferimento Oncologico Aviano (CRO), Istituto Nazionale Tumori, Italy.
Emanuela VaccherDepartment of Medical Oncology, Centro di Riferimento Oncologico Aviano (CRO), Istituto Nazionale Tumori, Italy.
Annunziata GloghiniDepartment of Diagnostic Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori Milano, Italy.
Liron PantanowitzDepartment of Pathology, University of Pittsburgh Medical Center, USA.
Akin AbayomiDepartment of Pathology, Division of Haematology, Tygerberg Hospital, South Africa.
Paolo de PaoliMolecular Virology and Scientific Directorate, Centro di Riferimento Oncologico Aviano (CRO), Istituto Nazionale Tumori, Italy.
Silvia FranceschiInfections and Cancer Epidemiology Group, International Agency for Research on Cancer, France.
Centro di Riferimento Oncologico · ITCentre International de Recherche sur le Cancer · FRFondazione IRCCS Istituto Nazionale dei Tumori · ITTygerberg Hospital · ZAUniversity of Pittsburgh Medical Center · US

Funding

World Health Organization 001
6 · The paper itself

Abstract

Despite the introduction of highly active antiretroviral therapy or combination antiretroviral therapy (HAART and cART, respectively) patients infected with HIV might develop certain types of cancer more frequently than uninfected people. Lymphomas represent the most frequent malignancy among patients with HIV. Other cancer types that have increased in these patients include Kaposi sarcoma, cancer of the cervix, anus, lung and liver. In the post-HAART era, however, patients with HIV have experienced a significant improvement in their morbidity, mortality and life expectancy. This Review focuses on the different types of lymphomas that generally occur in patients with HIV. The combination of cART and antineoplastic treatment has resulted in remarkable prolongation of disease-free survival and overall survival among patients with HIV who develop lymphoma. However, the survival in these patients still lags behind that of patients with lymphoma who are not infected with HIV. We also provide an update of epidemiological data, diagnostic issues, and strategies regarding the most-appropriate management of patients with both HIV and lymphomas.

Indexed as

Anti-HIV AgentsAntineoplastic Combined Chemotherapy ProtocolsCombined Modality TherapyDisease-Free SurvivalEarly Detection of CancerHIV InfectionsHumansImmunocompromised HostLymphoma, AIDS-RelatedNeoplasmsOncogenic VirusesOncolytic VirotherapyPeripheral Blood Stem Cell TransplantationSalvage TherapyT-LymphocytesAnti-HIV Agents

Identifiers

PMID24614140
OpenAlexW1986785799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.