Evidence map›Paper›PMID 24613678›Full record

ReviewMethods (San Diego, Calif.)2014

Detecting apoptosis in Drosophila tissues and cells.

Tatevik Sarkissian, Allison Timmons, Richa Arya, Eltyeb Abdelwahid, Kristin White

Abstract readReview
In one paragraph

Review in Methods (San Diego, Calif.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Olfactory inputs regulate Drosophila melanogaster oogenesis.The Journal of experimental biology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. A NovelInternational journal of molecular sciences · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Mutation and apoptosis are well-coordinated for protecting against DNA damage-inducing toxicity in Drosophila.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2023
    Article
  14. Extraembryonic tissue in chelicerates: a review and outlook.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Exploring Aβ Proteotoxicity and Therapeutic Candidates UsingInternational journal of molecular sciences · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tatevik SarkissianCBRC, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02129, USA.
Allison TimmonsDepartment of Biology, Boston University, Boston, MA 02215, USA.
Richa AryaCBRC, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02129, USA.
Eltyeb AbdelwahidCBRC, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02129, USA.
Kristin WhiteCBRC, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02129, USA. Electronic address: kristin.white@cbrc2.mgh.harvard.edu.

Funding

APOPTOSIS IN DROSOPHILA--FROM REAPER TO DEATHR01GM055568 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI WHITE, KRISTIN · 1997 to 2011
$3.8M
The regulation of cell death in vivoR01GM110477 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI WHITE, KRISTIN, ZHOU, LEI · 2015 to 2018
$1.4M
Nikon A1 laser scanning confocal microscope equipped for live imaging of cells anS10RR027673 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI WHITE, KRISTIN · 2010 to 2010
$500k
NCRR NIH HHS S10 RR027673NIGMS NIH HHS R01 GM055568NIGMS NIH HHS R01 GM110477NIGMS NIH HHS R01GM55568
6 · The paper itself

Abstract

In this chapter we discuss methods that can be used to study apoptotic cell death in the Drosophila embryo, ovary, as well as in cultured cell lines. These methods assay various aspects of the cell death process, from mitochondrial changes to caspase activation and DNA cleavage. The assays are useful for examining apoptosis in normal development and in response to developmental perturbations and external stresses. These techniques include Acridine Orange staining, TUNEL, cleaved caspase staining, caspase activity assays and assays for mitochondrial fission and permeabilization.

Indexed as

AnimalsApoptosisCaspasesDevelopmental BiologyDrosophilaMitochondriaPermeabilityCaspasesApoptosisCaspaseDrosophilaTUNEL

Identifiers

PMID24613678
PMCPMC4048790

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.