ArticleInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2014
Origin and characteristics of the recombinant novel avian infectious bronchitis coronavirus isolate ck/CH/LJL/111054.
Article in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 28 citations in OpenAlex.
- Molecular characteristics, phylodynamics, and evolutionary changes of avian infectious bronchitis virus detected from chickens in Yunnan Province, 2021-2024.Poultry science · 2026Article
- Discovery, phylogenetic, and comparative genomic analysis of novel avian gammacoronaviruses identified in feral pigeons (Journal of virology · 2025Article
- Unexplored viral diversity in Siberian cranes and wild geese: metagenomic insights from a global wintering haven.mSystems · 2025Article
- Genetic characterization of four strains porcine circovirus-like viruses in pigs with diarrhea in Hunan Province of China.Frontiers in microbiology · 2023Article
- Genetic and antigenic heterogeneity of GI-1/Massachusetts lineage infectious bronchitis virus variants recently isolated in China.Poultry science · 2020Article
- Multiple recombination events between field and vaccine strains resulted in the emergence of a novel infectious bronchitis virus with decreased pathogenicity and altered replication capacity.Poultry science · 2020Article
- Genetic diversity of avian infectious bronchitis virus in China in recent years.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2018Article
- Genetics, antigenicity and virulence properties of three infectious bronchitis viruses isolated from a single tracheal sample in a chicken with respiratory problems.Virus research · 2018Article
- Article
- Genome characterization, antigenicity and pathogenicity of a novel infectious bronchitis virus type isolated from south China.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2017Article
- Infectious Bronchitis Virus Variants: Molecular Analysis and Pathogenicity Investigation.International journal of molecular sciences · 2017Review
- Identification of a novel recombinant virulent avian infectious bronchitis virus.Veterinary microbiology · 2017Article
- Distribution of infectious bronchitis virus strains in different organs and evidence of vertical transmission in natural infection.Archives of virology · 2016Article
- Genome sequence and origin analyses of the recombinant novel IBV virulent isolate SAIBK2.Virus genes · 2016Article
- Recombinant duck enteritis viruses expressing major structural proteins of the infectious bronchitis virus provide protection against infectious bronchitis in chickens.Antiviral research · 2016Article
- Recombinant infectious bronchitis virus (IBV) H120 vaccine strain expressing the hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) protects chickens against IBV and NDV challenge.Archives of virology · 2016Article
- Altered pathogenicity of a tl/CH/LDT3/03 genotype infectious bronchitis coronavirus due to natural recombination in the 5'- 17kb region of the genome.Virus research · 2016Article
- Molecular and antigenic characteristics of Massachusetts genotype infectious bronchitis coronavirus in China.Veterinary microbiology · 2015Article
- Serotype shift of a 793/B genotype infectious bronchitis coronavirus by natural recombination.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2015Article
- Genomic and single nucleotide polymorphism analysis of infectious bronchitis coronavirus.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2015Article
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9 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Recombination among infectious bronchitis viruses (IBVs), coupled with point mutations, insertions, and deletions that occur in the genome, is thought to contribute to the emergence of new IBV variants. In this study an IBV, ck/CH/LJL/111054, was isolated from a H120-vaccinated chicken, which presented with a suspected IBV infection. Phylogenetic analysis of the S1 subunit sequence confirmed that strain ck/CH/LJL/111054 is of the Connecticut-type; however, further extensive full-length genomic analysis identified the occurrence of recombination events. Therefore, strain ck/CH/LJL/111054 may have originated from recombination events between Conn- and Mass-like strains at three recombination breakpoints: two located within the nsp3 gene sequence and one in the nsp12 gene sequence. Further, the uptake of the 5' untranslated regions, nsp2, parts of nsp3, nsp4-11, and parts of nsp 12 from Mass-like virus by ck/CH/LJL/111054 might have resulted in changes in viral replication efficiency rather than antigenic changes, via cross-neutralization analysis with the H120 strain. Recombination events coupled with the accumulation of mutations in the ck/CH/LJL/111054 genome may account for its increased virulence in specific-pathogen free chickens.
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