Evidence map›Paper›PMID 24613196›Full record

ArticleAnnals of epidemiology2014

Diabetes mellitus and risk of all-cause mortality among patients with tuberculosis in the state of Georgia, 2009-2012.

Matthew J Magee, Mary Foote, David M Maggio, Penelope P Howards, K M Venkat Narayan, Henry M Blumberg, Susan M Ray, Russell R Kempker

Open access · greenAbstract read
In one paragraph

Article in Annals of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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  18. Diabetes mellitus is associated with cavities, smear grade, and multidrug-resistant tuberculosis in Georgia.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2015
    Article
  19. Review
  20. Prevalence of Diabetes Mellitus and its Predictors among Tuberculosis Patients Currently on Treatment.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Matthew J MageeDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA. Electronic address: mjmagee@emory.edu.
Mary FooteDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA.
David M MaggioDivision of Health Protection, Georgia Department of Public Health, Atlanta, GA.
Penelope P HowardsDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.
K M Venkat NarayanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA; Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA.
Henry M BlumbergDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA; Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA.
Susan M RayDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA.
Russell R KempkerDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA.
Emory University · USGeorgia Department of Public Health · US

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
Intra Cavitary Pharmacokinetics and Drug Resistance in Pulmonary TuberculosisK23AI103044 · NIAID · EMORY UNIVERSITY · PI KEMPKER, RUSSELL RYAN · 2013 to 2017
$910k
FIC NIH HHS R25 TW009337NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1TR000454NIAID NIH HHS K23 AI103044NIAID NIH HHS K23AI103044
6 · The paper itself

Abstract

purposeTo estimate the association between diabetes mellitus (DM) and all-cause mortality during tuberculosis (TB) treatment.

methodsFrom 2009 to 2012, a retrospective cohort study among reported TB cases in Georgia was conducted. Patients aged 16 years or older were classified by DM and human immunodeficiency virus (HIV) status at the time of TB diagnosis and followed during TB treatment to assess mortality. Hazard ratios were used to estimate the association between DM and death.

resultsAmong 1325 patients with TB disease, 151 (11.4%) had DM, 147 (11.1%) were HIV-infected, and seven (0.5%) had both DM and HIV. Patients with TB-DM were more likely to have cavitary lung disease compared with those with TB alone (51.0% vs. 34.7%) and those with TB-HIV were more likely to have military/disseminated disease (12.9% vs. 3.4%) and resistance to rifampin or isoniazid (21.8% vs. 9.0%) compared with those without HIV infection (P < .05). In multivariable analysis, DM was not associated with death during TB treatment (hazard ratio, 1.22; 95% confidence interval, 0.70-2.12) or any death (adjusted odds ratio, 1.05; 95% confidence interval, 0.60-1.84).

conclusionsAmong TB patients in Georgia, the prevalence of comorbid DM and coinfection with HIV was nearly identical. In adjusted models, TB patients with DM did not have increased risk of all-cause mortality.

Indexed as

AdolescentAdultAgedAged, 80 and overAntitubercular AgentsCause of DeathCoinfectionComorbidityDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleFollow-Up StudiesGeorgiaHIV InfectionsHumansLogistic ModelsAntitubercular AgentsDiabetes mellitusGeorgiaHIVMortalityTuberculosis

Identifiers

PMID24613196
PMCPMC4011933
OpenAlexW2051860197

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.