ArticleBiological procedures online2014
Isolation of T cells from mouse oral tissues.
Article in Biological procedures online, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 20 citations in OpenAlex.
- Targeting IFN-I driven tertiary lymphoid structures halts B cell-mediated bone loss in periodontitis.International journal of oral science · 2026Article
- Type I interferon-induced CD169Journal of periodontology · 2026Article
- Differential Regulation of Innate Lymphoid Cells in Human and Murine Oral Squamous Cell Carcinoma.International journal of molecular sciences · 2023Article
- A gut-oral microbiome-driven axis controls oropharyngeal candidiasis through retinoic acid.JCI insight · 2022Article
- Cell specific variation in viability in suspension in in vitro Poiseuille flow conditions.Scientific reports · 2021Article
- An IL-17F.S65L Knock-In Mouse Reveals Similarities and Differences in IL-17F Function in Oral Candidiasis: A New Tool to Understand IL-17F.Journal of immunology (Baltimore, Md. : 1950) · 2020Article
- Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis.Science immunology · 2020Article
- IL-1β-MyD88-mTOR Axis Promotes Immune-Protective IL-17AFrontiers in immunology · 2020Article
- Microbiome Dependent Regulation of TFrontiers in immunology · 2019Review
- Mucosal HPV E6/E7 Peptide Vaccination in Combination with Immune Checkpoint Modulation Induces Regression of HPVCancer research · 2018Article
- Immune quiescence in the oral mucosa is maintained by a uniquely large population of highly activated Foxp3Mucosal immunology · 2018Article
- Article
- Phenotype and Tissue Residency of Lymphocytes in the Murine Oral Mucosa.Frontiers in immunology · 2017Article
- Origin and functions of pro-inflammatory cytokine producing Foxp3+ regulatory T cells.Cytokine · 2015Review
- TLR-2 Signaling Promotes IL-17A Production in CD4+CD25+Foxp3+ Regulatory Cells during Oropharyngeal Candidiasis.Pathogens (Basel, Switzerland) · 2015Article
- Th17 inflammation model of oropharyngeal candidiasis in immunodeficient mice.Journal of visualized experiments : JoVE · 2015Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundUtilizing mouse models provides excellent immunological and experimental tools to study oral immune responses. However for functional assays, isolating T lymphocytes from the oral tissues has proved to be challenging due to the absence of reliable methods that yield viable cells with consistency. To study adaptive immune cell interactions in the oral mucosal tissues, it is necessary to isolate T cells with a good viability and study them at the single cell level.
findingsWe have established an improved method to isolate immune cells, including Tregs and Th17 cells from intra-epithelial niches and lamina propria of the tongue, gingival and palatal tissues in the oral mucosa of mice.
conclusionThis new method of isolating immune cells from oral tissues will enable us to further our understanding of oral tissue immune cells and their role during oral infections and oral inflammation.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.