ArticleMolecular ecology2014
Evolutionary renovation of L/M opsin polymorphism confers a fruit discrimination advantage to ateline New World monkeys.
Article in Molecular ecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 82 citations in OpenAlex.
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- Spectral measurement of daylights and surface properties of natural objects in Japan.Optics express · 2022Article
- Color vision and niche partitioning in a diverse neotropical primate community in lowland Amazonian Ecuador.Ecology and evolution · 2021Article
- Short-wavelength-sensitive 2 (Sws2) visual photopigment models combined with atomistic molecular simulations to predict spectral peaks of absorbance.PLoS computational biology · 2020Article
- Orthologous Divergence and Paralogous Anticonvergence in Molecular Evolution of Triplicated Green Opsin Genes in Medaka Fish, Genus Oryzias.Genome biology and evolution · 2020Article
- Studying human and nonhuman primate evolutionary biology with powerful in vitro and in vivo functional genomics tools.Evolutionary anthropology · 2020Review
- Convergent spectral shifts to blue-green vision in mammals extends the known sensitivity of vertebrate M/LWS pigments.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Endocrine regulation of multichromatic color vision.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- As Blind as a Bat? Opsin Phylogenetics Illuminates the Evolution of Color Vision in Bats.Molecular biology and evolution · 2019Article
- Medium/Long wavelength sensitive opsin diversity in Pitheciidae.Scientific reports · 2017Article
- Howler monkey foraging ecology suggests convergent evolution of routine trichromacy as an adaptation for folivory.Ecology and evolution · 2017Article
- Novel opsin gene variation in large-bodied, diurnal lemurs.Biology letters · 2017Article
- Article
- Variation in ligand responses of the bitter taste receptors TAS2R1 and TAS2R4 among New World monkeys.BMC evolutionary biology · 2016Article
- Highly polymorphic colour vision in a New World monkey with red facial skin, the bald uakari (Cacajao calvus).Proceedings. Biological sciences · 2016Article
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Authors and funding
12 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
New World monkeys exhibit prominent colour vision variation due to allelic polymorphism of the long-to-middle wavelength (L/M) opsin gene. The known spectral variation of L/M opsins in primates is broadly determined by amino acid composition at three sites: 180, 277 and 285 (the 'three-sites' rule). However, two L/M opsin alleles found in the black-handed spider monkeys (Ateles geoffroyi) are known exceptions, presumably due to novel mutations. The spectral separation of the two L/M photopigments is 1.5 times greater than expected based on the 'three-sites' rule. Yet the consequence of this for the visual ecology of the species is unknown, as is the evolutionary mechanism by which spectral shift was achieved. In this study, we first examine L/M opsins of two other Atelinae species, the long-haired spider monkeys (A. belzebuth) and the common woolly monkeys (Lagothrix lagotricha). By a series of site-directed mutagenesis, we show that a mutation Y213D (tyrosine to aspartic acid at site 213) in the ancestral opsin of the two alleles enabled N294K, which occurred in one allele of the ateline ancestor and increased the spectral separation between the two alleles. Second, by modelling the chromaticity of dietary fruits and background leaves in a natural habitat of spider monkeys, we demonstrate that chromatic discrimination of fruit from leaves is significantly enhanced by these mutations. This evolutionary renovation of L/M opsin polymorphism in atelines illustrates a previously unappreciated dynamism of opsin genes in shaping primate colour vision.
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