ArticleJournal of veterinary internal medicine
DEA 1 expression on dog erythrocytes analyzed by immunochromatographic and flow cytometric techniques.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Frequency of erythrocyte antigen DEA 1 expression in dogs (Open veterinary journal · 2025Article
- Dog Blood Type DEA 1 in Two Municipalities of Luanda Province of Angola (Sub-Saharan Africa).Veterinary sciences · 2024Article
- Validation of a cage-side agglutination card for Dal blood typing in dogs.Journal of veterinary internal medicine · 2023Article
- Canine Blood Group Prevalence and Geographical Distribution around the World: An Updated Systematic Review.Animals : an open access journal from MDPI · 2021Review
- The dog erythrocyte antigen 1 blood group in nondomesticated canids and compatibility testing between domestic dog and nondomesticated canid blood.Journal of veterinary internal medicine · 2020Article
- Survey of Blood GroupsFrontiers in veterinary science · 2020Article
- Alloimmunization of a dog erythrocyte antigen 1- dog transfused with weakly dog erythrocyte antigen 1+ blood.Journal of veterinary internal medicine · 2019Article
- Modified stall-side crossmatch for transfusions in horses.Journal of veterinary internal medicine · 2019Article
- Detection of naturally occurring alloantibody by an in-clinic antiglobulin-enhanced and standard crossmatch gel column test in non-transfused domestic shorthair cats.Journal of veterinary internal medicine · 2019Article
- Naturally occurring antibodies in cats against dog erythrocyte antigens and vice versa.Journal of feline medicine and surgery · 2018Article
- Frequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALY.BMC veterinary research · 2017Article
- Pre- and Post-Transfusion Alloimmunization in Dogs Characterized by 2 Antiglobulin-Enhanced Cross-match Tests.Journal of veterinary internal medicine · 2017Article
- Kai 1 and Kai 2: Characterization of these dog erythrocyte antigens by monoclonal antibodies.PloS one · 2017Article
- Prevalence of Dog Erythrocyte Antigen 1 in 7,414 Dogs in Italy.Veterinary medicine international · 2017Article
- Survey of Two New (Kai 1 and Kai 2) and Other Blood Groups in Dogs of North America.Journal of veterinary internal medicine · 2016Article
- Xenotransfusion of anemic cats with blood compatibility issues: pre- and posttransfusion laboratory diagnostic and crossmatching studies.Veterinary clinical pathology · 2016Article
- Prevalence of Dog Erythrocyte Antigens 1, 4, and 7 in Podenco Ibicenco (Ibizan Hounds) from Ibiza Island.Veterinary medicine international · 2016Article
- Dog erythrocyte antigen 1: mode of inheritance and initial characterization.Veterinary clinical pathology · 2015Article
- Assessment of risks of feline mismatched transfusion and neonatal isoerythrolysis in the Lyon (France) area.JFMS open reportsArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe Dog erythrocyte antigen (DEA) 1 blood group system was thought to contain types DEA 1.1 and 1.2 (and possibly 1.3 [A3]). However, DEA 1.2+ dogs are very rare and newer typing methods reveal varying degrees of DEA 1 positivity.
objectivesTo assess if variation in DEA 1 positivity is because of quantitative differences in surface antigen expression. To determine expression patterns in dogs over time and effects of blood storage (4°C). To evaluate DEA 1.2+ samples by DEA 1 typing methods. ANIMALS: Anticoagulated blood samples from 66 dogs in a research colony and from a hospital, and 9 previously typed DEA 1.2+ dogs from an animal blood bank.
methodsResearch study: Samples were analyzed by flow cytometry and immunochromatographic strip using a monoclonal anti-DEA 1 antibody.
resultsTwenty dogs were DEA 1-, whereas 46 dogs were weakly to strongly DEA 1+. Antigen quantification revealed excellent correlation between strip and flow cytometry (r = 0.929). Both methods reclassified DEA 1.2+ samples as weakly to moderately DEA 1+, but they were not retyped with the polyclonal anti-DEA 1.1/1.X antibodies. Dogs and blood samples retained their relative DEA 1 antigen densities over time. CONCLUSIONS AND CLINICAL IMPORTANCE: The blood group system DEA 1 is a continuum from negative to strongly positive antigen expression. Previously typed DEA 1.2+ appears to be DEA 1+. These findings further the understanding of the DEA 1 system and suggest that all alleles within the DEA 1 system have a similarly based epitope recognized by the monoclonal antibody.
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