ArticleFrontiers in aging neuroscience2014
Gait disturbances as specific predictive markers of the first fall onset in elderly people: a two-year prospective observational study.
Article in Frontiers in aging neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 56 citations in OpenAlex.
- Trunk motion visual feedback during walking improves dynamic balance in older adults: Assessor blinded randomized controlled trial.Gait & posture · 2018Trial
- Prospective gait analysis in patients from the French registry of glycogen storage disease type III: implications for clinical trials.Journal of neurology · 2026Article
- Evaluation of instability in patients with chronic vestibular syndrome using dynamic stability indicators.Medical & biological engineering & computing · 2025Article
- Gait Characterization in Duchenne Muscular Dystrophy (DMD) Using a Single-Sensor Accelerometer: Classical Machine Learning and Deep Learning Approaches.Sensors (Basel, Switzerland) · 2024Article
- Effect of heel lift insertion on gait function in a patient with total hip arthroplasty with patient-perceived leg length difference: a case report.Journal of physical therapy science · 2024Article
- Fear of falling in community-dwelling older adults: What their gait acceleration pattern reveals.Computer methods and programs in biomedicine · 2024Article
- Relationship between Muscle Strength and Gait Parameters in Healthy Older Women and Men.International journal of environmental research and public health · 2023Article
- Impact of walking states, self-reported daily walking amount and age on the gait of older adults measured with a smart-phone app: a pilot study.BMC geriatrics · 2022Article
- Relationships between Gait Regularity and Cognitive Function, including Cognitive Domains and Mild Cognitive Impairment, in Community-Dwelling Older People.Healthcare (Basel, Switzerland) · 2021Article
- Wearable Feet Pressure Sensor for Human Gait and Falling Diagnosis.Sensors (Basel, Switzerland) · 2021Article
- Relationship of the sacral slope with early gait derangements in robust older women.Advances in rheumatology (London, England) · 2021Article
- The Prevalence and Negative Effects of Thoracic Hyperkyphosis on Chinese Community-Dwelling Older Adults in Wuhan, Hubei Province, China.The journal of nutrition, health & aging · 2021Article
- Review
- Design and Evaluation of an Augmented Reality-Based Exergame System to Reduce Fall Risk in the Elderly.International journal of environmental research and public health · 2020Article
- Postadychute-AG, Detection, and Prevention of the Risk of Falling Among Elderly People in Nursing Homes: Protocol of a Multicentre and Prospective Intervention Study.Frontiers in digital health · 2020Article
- Assessing gait parameters with accelerometer-based methods to identify older adults at risk of falls: a systematic review.European geriatric medicine · 2018Review
- Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.GeroScience · 2017Article
- Feature selection for elderly faller classification based on wearable sensors.Journal of neuroengineering and rehabilitation · 2017Article
- Gait disorders in the elderly and dual task gait analysis: a new approach for identifying motor phenotypes.Journal of neuroengineering and rehabilitation · 2017Observational
- Continuous Monitoring of Turning Mobility and Its Association to Falls and Cognitive Function: A Pilot Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Falls are common in the elderly, and potentially result in injury and disability. Thus, preventing falls as soon as possible in older adults is a public health priority, yet there is no specific marker that is predictive of the first fall onset. We hypothesized that gait features should be the most relevant variables for predicting the first fall. Clinical baseline characteristics (e.g., gender, cognitive function) were assessed in 259 home-dwelling people aged 66 to 75 that had never fallen. Likewise, global kinetic behavior of gait was recorded from 22 variables in 1036 walking tests with an accelerometric gait analysis system. Afterward, monthly telephone monitoring reported the date of the first fall over 24 months. A principal components analysis was used to assess the relationship between gait variables and fall status in four groups: non-fallers, fallers from 0 to 6 months, fallers from 6 to 12 months and fallers from 12 to 24 months. The association of significant principal components (PC) with an increased risk of first fall was then evaluated using the area under the Receiver Operator Characteristic Curve (ROC). No effect of clinical confounding variables was shown as a function of groups. An eigenvalue decomposition of the correlation matrix identified a large statistical PC1 (termed "Global kinetics of gait pattern"), which accounted for 36.7% of total variance. Principal component loadings also revealed a PC2 (12.6% of total variance), related to the "Global gait regularity." Subsequent ANOVAs showed that only PC1 discriminated the fall status during the first 6 months, while PC2 discriminated the first fall onset between 6 and 12 months. After one year, any PC was associated with falls. These results were bolstered by the ROC analyses, showing good predictive models of the first fall during the first six months or from 6 to 12 months. Overall, these findings suggest that the performance of a standardized walking test at least once a year is essential for fall prevention.
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