ArticleThe Plant cell2014
Arabidopsis CAM7 and HY5 physically interact and directly bind to the HY5 promoter to regulate its expression and thereby promote photomorphogenesis.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
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Who cites it
93 citing papers in PubMed.
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- Functional Characterisation of NF-YCs in True Leaf Biomass Accumulation.Plants (Basel, Switzerland) · 2026Article
- TCP21 negatively regulates photomorphogenesis by integrating phyB- and HY5-mediated signaling pathways in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- PtrbZIP12 improves drought resistance inHorticulture research · 2026Article
- Transcriptome Reveals Growth Responses ofBiology · 2025Article
- Transcriptomic analysis reveals the growth of Populus Schneideri in different light qualities.BMC genomics · 2025Article
- Threshold-dependent negative autoregulation of PIF4 gene expression optimizes growth and fitness in Arabidopsis.PLoS genetics · 2025Article
- Transcriptome and 2-DE proteome analyses reveal defense-associated development in the leaf galls induced by psyllids on Machilus japonica var. kusanoi.Botanical studies · 2025Article
- Decoding Long-Distance Communication Under Mineral Stress: Advances in Vascular Signalling and Molecular Tools for Plant Resilience.Plant, cell & environment · 2025Review
- The PpAHL17-PpHYH module is involved in light-independent anthocyanin accumulation in fruit peel of Prunus persica.Plant cell reports · 2025Article
- CaBMC plant biology · 2025Article
- Unequal Genetic Redundancies Among MYC bHLH Transcription Factors Underlie Seedling Photomorphogenesis in Arabidopsis.Plant direct · 2025Article
- The Vital Role of theInternational journal of molecular sciences · 2024Article
- Ubiquitin-specific protease UBP14 stabilizes HY5 by deubiquitination to promote photomorphogenesis inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Exploring the interplay between angiosperm chlorophyll metabolism and environmental factors.Planta · 2024Review
- Allelic variation of BBX24 is a dominant determinant controlling red coloration and dwarfism in pear.Plant biotechnology journal · 2024Article
- A Regulatory Mechanism on Pathways: Modulating Roles of MYC2 and BBX21 in the Flavonoid Network.Plants (Basel, Switzerland) · 2024Article
- Identification and validation of seed dormancy loci and candidate genes and construction of regulatory networks by WGCNA in maize introgression lines.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Environmental Stimuli and Phytohormones in Anthocyanin Biosynthesis: A Comprehensive Review.International journal of molecular sciences · 2023Review
33 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
Arabidopsis thaliana CALMODULIN7 (CAM7), a unique member of the calmodulin gene family, plays a crucial role as a transcriptional regulator in seedling development. The elongated HYPOCOTYL5 (HY5) bZIP protein, an integrator of multiple signaling pathways, also plays an important role in photomorphogenic growth and light-regulated gene expression. CAM7 acts synergistically with HY5 to promote photomorphogenesis at various wavelengths of light. Although the genetic relationships between CAM7 and HY5 in light-mediated seedling development have been demonstrated, the molecular connectivity between CAM7 and HY5 is unknown. Furthermore, whereas HY5-mediated gene regulation has been fairly well investigated, the transcriptional regulation of HY5 is largely unknown. Here, we report that HY5 expression is regulated by HY5 and CAM7 at various wavelengths of light and also at various stages of development. In vitro and in vivo DNA-protein interaction studies suggest that HY5 and CAM7 bind to closely located T/G- and E-box cis-acting elements present in the HY5 promoter, respectively. Furthermore, CAM7 and HY5 physically interact and regulate the expression of HY5 in a concerted manner. Taken together, these results demonstrate that CAM7 and HY5 directly interact with the HY5 promoter to mediate the transcriptional activity of HY5 during Arabidopsis seedling development.
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