SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2014
The effectiveness and safety of moxibustion for treating cancer-related fatigue: a systematic review and meta-analyses.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Efficacy and safety of moxibustion on cancer-related fatigue: a systematic review and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- Effectiveness of acupuncture and related therapies for palliative care of cancer: overview of systematic reviews.Scientific reports · 2015Pooled it
- Efficacy of Moxibustion for Cancer-Related Fatigue in Patients with Breast Cancer: A Systematic Review and Meta-Analysis.Integrative cancer therapiesPooled it
- An Overview of Systematic Reviews: Complementary Therapies for Cancer Patients.Integrative cancer therapiesPooled it
- Effects of 3.95 μm infrared moxibustion on cancer-related fatigue: a randomized, controlled trial.Lasers in medical science · 2025Trial
- Moxibustion for treating cancer-related fatigue: A multicenter, assessor-blinded, randomized controlled clinical trial.Cancer medicine · 2021Trial
- Moxibustion for cancer-related fatigue: study protocol for a randomized controlled trial.BMC complementary and alternative medicine · 2017Trial
- Trial
- Moxibustion for gastrointestinal cancer-related fatigue: study protocol for a randomized clinical trial.Frontiers in psychiatry · 2026Article
- Effect of Electronic Moxibustion in Patients with IDH: A Randomized Crossover Pilot Study.International journal of general medicine · 2024Article
- AI Chat bot - ChatGPT-4: A new opportunity and challenges in complementary and alternative medicine (CAM).Integrative medicine research · 2023Article
- Zhengyuan capsules for the treatment of chemotherapy-induced cancer-related fatigue in stage IIIB-IV unresectable NSCLC: study protocol for a randomized, multi-center, double-blind, placebo-controlled clinical trial.Journal of thoracic disease · 2022Article
- Acupuncture and Moxibustion for Cancer-Related Fatigue: An Overview of Systematic Reviews and Meta-Analysis.Cancers · 2022Review
- Cortisol Secretion and Subsequent Impaired Lymphopoiesis after Starvation Can Be Reduced by Moxibustion Treatment.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Article
- Article
- Nutritional Interventions for Treating Cancer-Related Fatigue: A Qualitative Review.Nutrition and cancer · 2019Review
- Add-On Complementary Medicine in Cancer Care: Evidence in Literature and Experiences of Integration.Medicines (Basel, Switzerland) · 2017Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAmong cancer patients, cancer-related fatigue (CRF) is one of the most common symptoms and adversely affects physical ability and quality of life even several years after treatment. This study aims to evaluate the current evidence for moxibustion in patients with CRF.
methodsEighteen databases were searched from their inception to April 2013. All randomized controlled trials (RCTs) of moxibustion for treating CRF without language restriction were considered for inclusion. The risk of bias and reporting quality of each study were assessed using the Cochrane risk of bias tool, Consolidated Standards of Reporting Trials (CONSORT), and Revised Standards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA). Risk ratio (RR) or mean difference (MD) was used to measure the treatment effect with 95 % confidence intervals (CIs) in a random effects model.
resultsFour RCTs with a total of 374 subjects were included for the review. These four studies compared moxibustion plus routine care with routine care alone. Most studies were determined to have a moderate to high risk of bias with low reporting quality. An indirect moxa stick was used in two studies, an indirect ginger cake-separated moxa was used in one study, and in one remaining study, both moxibustion methods were used. Meta-analysis showed the favorable effects of moxibustion on the response rate (RR, 1.73; 95 % CI, 1.29 to 2.32; p=.0003; heterogeneity, I (2)=15 %, p=.32). Burning with a mild blister after moxibustion was reported in one study.
conclusionsBecause of a high risk of bias and low reporting quality of the studies included in this review, it is difficult to draw the conclusion that moxibustion is an effective and safe treatment for patients with CRF. Further rigorous research will be necessary to evaluate whether moxibustion has beneficial effects on CRF.
trial registrationPROSPERO. Unique identifier: CRD42013004501.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.