Evidence map›Paper›PMID 24609453›Full record

ReviewSchizophrenia bulletin2014

A systems neuroscience perspective of schizophrenia and bipolar disorder.

Sophia Frangou

Open access · bronzeAbstract readReview
In one paragraph

Review in Schizophrenia bulletin, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Neuroprogression across the Early Course of Psychosis.Journal of psychiatry and brain science · 2020
    Article
  13. Article
  14. Structural Brain Alterations in Youth With Psychosis and Bipolar Spectrum Symptoms.Journal of the American Academy of Child and Adolescent Psychiatry · 2019
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Aberrant cerebellar connectivity in bipolar disorder with psychosis.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Sophia Frangou*To whom correspondence should be addressed; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, US; tel: 212-659-1668, fax: 212-659-8576, e-mail: sophia.frangou@mssm.edu.
Icahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroimaging studies have generated a large body of knowledge regarding the neural correlates of schizophrenia (SZ) and bipolar disorder (BD). However, the initial goal of identifying disease-specific topographical mappings to localized brain regions or to distinct neural networks has not materialized and may be untenable. This contribution will argue that a systems neuroscience approach may prove more fruitful. The supporting evidence presented covers (a) brain structural, functional, and connectivity alterations and their implication for the clinical and cognitive manifestations of SZ and BD, (b) the prevailing system neuroscience models of the 2 disorders, and (c) key hypotheses likely to produce new insights into the mechanisms of underlying psychotic disorders.

Indexed as

Bipolar DisorderBrainBrain MappingFunctional NeuroimagingHumansModels, BiologicalNeural PathwaysSchizophreniaSystems Biologybipolar disorderneuroimagingschizophrenia

Identifiers

PMID24609453
PMCPMC3984528
OpenAlexW2157223246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.