Evidence map›Paper›PMID 24608864›Full record

Trial reportPloS one2014

Conventional vs. tablet computer-based patient education following lung transplantation--a randomized controlled trial.

Hendrik Suhling, Jessica Rademacher, Imke Zinowsky, Jan Fuge, Mark Greer, Gregor Warnecke, Jacqueline M Smits, Anna Bertram, Axel Haverich, Tobias Welte and 1 more

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01398488 (Patient Education After Lung Transplantation Via Tablet Computers Versus Conventional Education - a Randomized Open Controlled Trial), which is not on this map. Cited by 24 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01398488 phase2completednot on this map

Patient Education After Lung Transplantation Via Tablet Computers Versus Conventional Education - a Randomized Open Controlled Trial

TypeinterventionalSponsorHannover Medical SchoolRan2011 to 2013Enrolled64ConditionsLung TransplantationArmsPatient education
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  3. mHealth education interventions in heart failure.The Cochrane database of systematic reviews · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hendrik SuhlingDept. of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Jessica RademacherDept. of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Imke ZinowskyDept. of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Jan FugeDept. of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Mark GreerDept. of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Gregor WarneckeDept. of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Jacqueline M SmitsEurotransplant International Foundation, Leiden, The Netherlands.
Anna BertramDept. of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.
Axel HaverichDept. of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Tobias WelteDept. of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Jens GottliebDept. of Respiratory Medicine, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate immunosuppression is of critical importance in preventing rejection, while avoiding toxicity following lung transplantation. The mainstay immunosuppressants are calcineurin inhibitors, which require regular monitoring due to interactions with other medications and diet. Adherence to immunosuppression and patient knowledge is vital and can be improved through patient education. Education using tablet-computers was investigated.

objectiveTo compare tablet-PC education and conventional education in improving immunosuppression trough levels in target range 6 months after a single education. Secondary parameters were ratio of immunosuppression level measurements divided by per protocol recommended measurements, time and patient satisfaction regarding education.

designSingle-centre, open labelled randomised controlled trial.

participantsPatients >6 months after lung-transplantation with <50% of calcineurin inhibitor trough levels in target range.

interventionTablet-pc education versus personal, nurse-led education. MEASUREMENTS: Calcineurin inhibitor levels in target range 6 months after education, level variability, interval adherence, knowledge and adherence was studied. As outcome parameter, renal function was measured and adverse events registered.

resultsSixty-four patients were 1:1 randomised for either intervention. Levels of immunosuppression 6 months after education were equal (tablet-PC 58% vs. conventional 48%, p = 0.27), both groups improved in achieving a CNI trough level within target range by either education method (delta tablet-PC 29% vs. conventional 20%). In all patients, level variability decreased (-20.4%), whereas interval adherence remained unchanged. Knowledge about immunosuppression improved by 7% and compliance tests demonstrated universal improvements with no significant difference between groups.

conclusionEducation is a simple, effective tool in improving adherence to immunosuppression. Tablet-PC education was non-inferior to conventional education.

trial registrationClinicalTrials.gov NCT01398488 http://clinicaltrials.gov/ct2/show/NCT01398488? term=gottlieb+tablet+pc+education&rank=1.

Indexed as

AdultCalcineurin InhibitorsComputers, HandheldGraft RejectionHumansImmunosuppression TherapyImmunosuppressive AgentsLung TransplantationMiddle AgedPatient Education as TopicCalcineurin InhibitorsImmunosuppressive Agents

Identifiers

PMID24608864
PMCPMC3946627

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.