ArticlePloS one2014
Proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 49 citations in OpenAlex.
- Mating system variation and gene expression in the male reproductive tract of Peromyscus mice.Molecular ecology · 2025Article
- Expression, Localization, and Processing of Chicken Sperm ADAM32L2 during the Acrosome Reaction: A Possible Function in the Sperm-Egg Interaction.The journal of poultry science · 2025Article
- Convergent rates of protein evolution identify novel targets of sexual selection in primates.Evolution; international journal of organic evolution · 2024Article
- Signatures of selection inEvolutionary applications · 2024Article
- The Role of Sperm Membrane Potential and Ion Channels in Regulating Sperm Function.International journal of molecular sciences · 2023Review
- Haploid and Sexual Selection Shape the Rate of Evolution of Genes across the Honey Bee (Apis mellifera L.) Genome.Genome biology and evolution · 2022Article
- Sperm bauplan and function and underlying processes of sperm formation and selection.Physiological reviews · 2022Review
- Ancestral Sperm Ecotypes Reveal Multiple Invasions of a Non-Native Fish in Northern Europe.Cells · 2021Article
- Cold-Shock Test Is a Practical Method for Selecting Boar Ejaculates Yielding Appropriate Seminal Plasma for Post-Thawing Supplementation.Animals : an open access journal from MDPI · 2021Article
- CRISPs Function to Boost Sperm Power Output and Motility.Frontiers in cell and developmental biology · 2021Article
- Proteomic Changes Associated With Sperm Fertilizing Ability in Meat-Type Roosters.Frontiers in cell and developmental biology · 2021Article
- Transcriptional activity and strain-specific history of mouse pseudogenes.Nature communications · 2020Article
- Evolutionary analysis of genes coding for Cysteine-RIch Secretory Proteins (CRISPs) in mammals.BMC evolutionary biology · 2020Article
- Sperm Differentiation: The Role of Trafficking of Proteins.International journal of molecular sciences · 2020Review
- Gene Polymorphisms in Boar Spermatozoa and Their Associations with Post-Thaw Semen Quality.International journal of molecular sciences · 2020Article
- Effect of Exposure to Seminal Plasma Through Natural Mating in Cattle on Conceptus Length and Gene Expression.Frontiers in cell and developmental biology · 2020Article
- Selection shapes turnover and magnitude of sex-biased expression in Drosophila gonads.BMC evolutionary biology · 2019Article
- RNA-seq coupled to proteomic analysis reveals high sperm proteome variation between two closely related marine mussel species.Journal of proteomics · 2019Article
- Positive Selection in the Evolution of Mammalian CRISPs.Journal of molecular evolution · 2018Article
- Correlates of evolutionary rates in the murine sperm proteome.BMC evolutionary biology · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proteomic studies of spermatozoa have identified a large catalog of integral sperm proteins. Rapid evolution of these proteins may underlie adaptive changes of sperm traits involved in different events leading to fertilization, although the selective forces underlying such rapid evolution are not well understood. A variety of selective forces may differentially affect several steps ending in fertilization, thus resulting in a compartmentalized adaptation of sperm proteins. Here we analyzed the evolution of genes associated to various events in the sperm's life, from sperm formation to sperm-egg interaction. Evolutionary analyses were performed on gene sequences from 17 mouse strains whose genomes have been sequenced. Four of these are derived from wild Mus musculus, M. domesticus, M. castaneus and M. spretus. We found a higher proportion of genes exhibiting a signature of positive selection among those related to sperm motility and sperm-egg interaction. Furthermore, sperm proteins involved in sperm-egg interaction exhibited accelerated evolution in comparison to those involved in other events. Thus, we identified a large set of candidate proteins for future comparative analyses of genotype-phenotype associations in spermatozoa of species subjected to different sexual selection pressures. Adaptive evolution of proteins involved in motility could be driven by sperm competition, since this selective force is known to increase the proportion of motile sperm and their swimming velocity. On the other hand, sperm proteins involved in gamete interaction could be coevolving with their egg partners through episodes of sexual selection or sexual conflict resulting in species-specific sperm-egg interactions and barriers preventing interspecies fertilization.
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