ArticleAmerican journal of obstetrics and gynecology2014
Risk of late-preterm stillbirth and neonatal morbidity for monochorionic and dichorionic twins.
Article in American journal of obstetrics and gynecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Global prevalence of stillbirth among fetuses from twin pregnancies: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2025Pooled it
- Timing of Delivery for Twins With Growth Discordance and Growth Restriction: An Individual Participant Data Meta-analysis.Obstetrics and gynecology · 2022Pooled it
- Vaginal progesterone decreases preterm birth and neonatal morbidity and mortality in women with a twin gestation and a short cervix: an updated meta-analysis of individual patient data.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2017Pooled it
- Prospective risk of stillbirth and neonatal complications in twin pregnancies: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2016Pooled it
- Trial
- Society for Maternal-Fetal Medicine Special Statement: Updated checklists for management of monochorionic twin pregnancy.Pregnancy (Hoboken, N.J.) · 2026Article
- Feeding challenges in larger versus smaller preterm discordant twins.Frontiers in pediatrics · 2026Article
- Case Report: Missed diagnosis of twin reversed arterial perfusion sequence discovered at delivery: lessons from poorly monitored monochorionic twin pregnancy.Frontiers in medicine · 2026Article
- Universal cervical-length screening to prevent preterm birth in twin pregnancy: cost-utility analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025Article
- The sFlt-1/PlGF Ratio at 12, 24, and 32 Weeks Gestation in Twin Pregnancies as a Predictor of Late Preterm Birth and Perinatal Event Secondary to Prematurity.Journal of clinical medicine · 2024Article
- Is the Early Screening of Lower Genital Tract Infections Useful in Preventing Adverse Obstetrical Outcomes in Twin Pregnancy?Journal of clinical medicine · 2024Article
- Induction of Labour. Guideline of the DGGG, OEGGG and SGGG (S2k, AWMF Registry No. 015-088, December 2020).Geburtshilfe und Frauenheilkunde · 2021Article
- Should singleton birth weight standards be applied to identify small-for-gestational age twins?: analysis of a retrospective cohort study.BMC pregnancy and childbirth · 2021Article
- Perinatal Outcomes of Small for Gestational Age in Twin Pregnancies: Twin vs. Singleton Charts.Journal of clinical medicine · 2021Article
- Delivery timing after laser surgery for twin-twin transfusion syndrome.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- How does gestational age affect growth and body composition of preterm twins?Pediatric research · 2020Article
- Twin Pregnancy in Brazil: A Profile Analysis Exploring Population Information from the National Birth E-Registry on Live Births.BioMed research international · 2018Article
- Comparison of perinatal outcomes in late preterm birth between singleton and twin pregnancies.Obstetrics & gynecology science · 2017Article
- Do serial measurements of cervical length improve the prediction of preterm birth in asymptomatic women with twin gestations?American journal of obstetrics and gynecology · 2016Article
- Serial cervical length determination in twin pregnancies reveals 4 distinct patterns with prognostic significance for preterm birth.American journal of obstetrics and gynecology · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveThe purpose of this study was to determine the prospective risk of intrauterine fetal death (IUFD) at ≥34 weeks' gestation for monochorionic and dichorionic twins receiving intensive antenatal fetal surveillance. The secondary objective was to calculate the incidence of prematurity-related neonatal morbidity/mortality rates that have been stratified by gestational week and chorionicity. STUDY
designA retrospective cohort study of all twins at ≥34 weeks' gestation who were delivered at the Medical University of South Carolina (1987-2010) was performed. Twins were cared for in a longstanding Twin Clinic with standardized treatment and surveillance protocols and supervised by a consistent Maternal-Fetal Medicine specialist. Gestational age-specific fetal/neonatal mortality rates and composite neonatal morbidity rates were compared by chorionicity. A generalized linear mixed model was used to identify variables that were associated with increased composite neonatal morbidity.
resultsAmong 768 twin gestations (601 dichorionic and 167 monochorionic), only 1 dichorionic IUFD occurred. The prospective risk of IUFD at ≥34 weeks' gestation was 0.17% for dichorionic twins and 0% for monochorionic twins. Composite neonatal morbidity decreased with each gestational week (P < .0001). Morbidity was increased by white race, gestational diabetes mellitus, and elective indication for delivery. The nadir of composite neonatal morbidity occurred at 36/0-36/6 weeks' gestation for monochorionic twins and 37/0-37/6 weeks' gestation for dichorionic twins.
conclusionOur data do not support concern for an increased risk of stillbirth in uncomplicated intensively monitored monochorionic twins at ≥34 weeks' gestation. However, our data do show significantly increased rates of neonatal morbidity in late preterm monochorionic twins that cannot be justified by a corresponding reduction in the risk of stillbirth. We believe that our data support delivery of uncomplicated monochorionic twins at 37 weeks' gestation.
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Registered trials
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