Evidence map›Paper›PMID 24607755›Full record

Trial reportAmerican journal of obstetrics and gynecology2014

Delivery timing and cesarean delivery risk in women with mild gestational diabetes mellitus.

Amelia L Sutton, Lisa Mele, Mark B Landon, Susan M Ramin, Michael W Varner, John M Thorp, Anthony Sciscione, Patrick Catalano, Margaret Harper, George Saade and 4 more

Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in American journal of obstetrics and gynecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00069576 (A Randomized Clinical Trial of Treatment for Mild Gestational Diabetes Mellitus), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00069576 nacompletednot on this map

A Randomized Clinical Trial of Treatment for Mild Gestational Diabetes Mellitus

TypeinterventionalSponsorThe George Washington University Biostatistics CenterRan2002 to 2013Enrolled7,381ConditionsDiabetes, GestationalArmsnutritional counseling, self blood glucose monitoring
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Diabetes mellitus: an independent predictor of duration of prostaglandin labor induction.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Trial
  5. [Management of hyperglycemia in pregnancy (Update 2026)].Wiener klinische Wochenschrift · 2026
    Review
  6. Review
  7. [Gestational diabetes mellitus (Update 2023)].Wiener klinische Wochenschrift · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. [Gestational diabetes mellitus (Update 2019)].Wiener klinische Wochenschrift · 2019
    Review
  13. Article
  14. Article
  15. Timing of delivery and pregnancy outcomes in women with gestational diabetes.American journal of obstetrics and gynecology · 2016
    Article
  16. Timing of Delivery in Gestational Diabetes Mellitus: Need for Person-Centered, Shared Decision-Making.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2016
    Article
  17. Labor and neonatal outcomes after term induction of labor in gestational diabetes.Journal of perinatology : official journal of the California Perinatal Association · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 13 institutions in 1 country.

Amelia L SuttonDepartments of Obstetrics and Gynecology of the University of Alabama at Birmingham, Birmingham, AL.
Lisa MeleGeorge Washington University Biostatistics Center, Washington, DC.
Mark B LandonThe Ohio State University, Columbus, OH.
Susan M RaminUniversity of Texas Health Science Center at Houston, Houston, TX.
Michael W VarnerUniversity of Utah School of Medicine, Salt Lake City, UT.
John M ThorpUniversity of North Carolina, Chapel Hill, School of Medicine, Chapel Hill, NC.
Anthony SciscioneDrexel University, Philadelphia, PA.
Patrick CatalanoCase Western Reserve University School of Medicine-MetroHealth Medical Center, Cleveland, OH.
Margaret HarperWake Forest University Health Sciences, Winston-Salem, NC.
George SaadeUniversity of Texas Medical Branch School of Medicine, Galveston, TX.
Steve N CaritisUniversity of Pittsburgh, Pittsburgh, PA.
Yoram SorokinWayne State University, Detroit, MI.
William A GrobmanFeinberg School of Medicine, Northwestern University, Chicago, IL.
Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
Drexel University · USGeorge Washington University · USMetroHealth · USNorthwestern University · USThe Ohio State University · USThe University of Texas Health Science Center at Houston · USThe University of Texas Medical Branch at Galveston · USUniversity of Alabama at Birmingham · USUniversity of North Carolina at Chapel Hill · USUniversity of Pittsburgh · USUniversity of Utah · USWake Forest University · USWayne State University · US

Funding

Data Coord Ctr-NICHD Cooperative Multicenter Maternal Medicine Units Research NetU10HD036801 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI CLIFTON, REBECCA GERSNOVIEZ · 2009 to 2021
$174.2M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024989 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI DAVIS, PAMELA B · 2007 to 2011
$53.7M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
SARS-CoV-2 Vaccine Pregnancy RegistryU24HD036801 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI Rebecca Gersnoviez Clifton · 2021 to 2026
$39.2M
MATERNAL FETAL RESEARCH NETWORK: DATA COORDINATING CTRU01HD036801 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI THOM, ELIZABETH ANN · 1998 to 2008
$27.0M
YOGA, IMMUNE FUNCTION, AND HEALTHM01RR000034 · NCRR · OHIO STATE UNIVERSITY · PI PESAVENTO, TODD · 1985 to 2008
$22.7M
The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
Zosuquidar trihydrochloride for acute myeloid leukemia &refractory anemiaM01RR000080 · NCRR · UNIVERSITY HOSPITALS OF CLEVELAND · PI DAVIS, PAMELA B · 1985 to 2007
$22.2M
UNIVERSITY OF UTAH CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE-UL1: BPCAUL1RR025764 · NCRR · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2008 to 2011
$19.4M
NICHD Maternal Fetal Medicine Units NetworkU10HD034116 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI CASEY, BRIAN M · 1996 to 2015
$19.3M
NICHD Maternal Fetal Medicine Units NetworkU10HD034208 · NICHD · UNIVERSITY OF UTAH · PI VARNER, MICHAEL W. · 1996 to 2015
$16.6M
NICHD Maternal Fetal Medicine Units NetworkU10HD027869 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TITA, ALAN THEVENET N. · 1991 to 2015
$12.8M
NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1 TR001070NCRR NIH HHS C06 RR011234NCRR NIH HHS M01 RR000034NCRR NIH HHS M01 RR000080NCRR NIH HHS M01-RR00034NCRR NIH HHS M01-RR00080NCRR NIH HHS UL1 RR024989NCRR NIH HHS UL1-RR024989NCRR NIH HHS UL1 RR025764NCRR NIH HHS UL1-RR025764NICHD NIH HHS HD21410NICHD NIH HHS HD27860NICHD NIH HHS HD27869NICHD NIH HHS HD27915NICHD NIH HHS HD27917NICHD NIH HHS HD34116NICHD NIH HHS HD34136NICHD NIH HHS HD34208NICHD NIH HHS HD36801NICHD NIH HHS HD40485NICHD NIH HHS HD40500NICHD NIH HHS HD40512NICHD NIH HHS HD40544NICHD NIH HHS HD40545NICHD NIH HHS HD40560NICHD NIH HHS HD53097NICHD NIH HHS HD53118NICHD NIH HHS P2C HD050924NICHD NIH HHS U01 HD036801NICHD NIH HHS U10 HD021410NICHD NIH HHS U10 HD027860NICHD NIH HHS U10 HD027869NICHD NIH HHS U10 HD027915NICHD NIH HHS U10 HD027917NICHD NIH HHS U10 HD034116NICHD NIH HHS U10 HD034136NICHD NIH HHS U10 HD034208NICHD NIH HHS U10 HD036801NICHD NIH HHS U10 HD040485NICHD NIH HHS U10 HD040500NICHD NIH HHS U10 HD040512NICHD NIH HHS U10 HD040544NICHD NIH HHS U10 HD040545NICHD NIH HHS U10 HD040560NICHD NIH HHS U10 HD053097NICHD NIH HHS U10 HD053118NICHD NIH HHS U24 HD036801NICHD NIH HHS UG1 HD027869NICHD NIH HHS UG1 HD027915NICHD NIH HHS UG1 HD034116NICHD NIH HHS UG1 HD034208NICHD NIH HHS UG1 HD040485NICHD NIH HHS UG1 HD040500NICHD NIH HHS UG1 HD040512NICHD NIH HHS UG1 HD040544NICHD NIH HHS UG1 HD040545NICHD NIH HHS UG1 HD040560NICHD NIH HHS UG1 HD053097
6 · The paper itself

Abstract

objectiveThe purpose of this study was to evaluate the relationship between gestational age (GA) and induction of labor (IOL) and the rate of cesarean delivery in women with mild gestational diabetes mellitus. STUDY

designWe conducted a secondary analysis of data from a multicenter randomized controlled trial of mild gestational diabetes mellitus treatment. Cesarean delivery rate of women delivering at term (≥37 weeks' gestation) was evaluated by 2 complementary approaches: (1) IOL vs spontaneous labor: women who were induced at each GA compared with those who spontaneously labored at the same GA and (2) IOL vs expectant management: women who delivered after IOL at each GA compared with those who delivered after spontaneous labor at the same GA or subsequently after spontaneous or induced labor (outcome at each week compared with expectant management at that week). Logistic regression adjusted for potential confounders.

resultsThe overall cesarean delivery rate was 13%. When compared with 39 weeks' gestation (either IOL or spontaneous labor) as the referent, there was no significant difference in the cesarean delivery rate in women who delivered at 37, 38, or 40 weeks' gestation. However, IOL was associated with a 3-fold increase in cesarean delivery rate at 41 weeks' gestation and beyond, as compared with IOL at 39 weeks' gestation. Similarly, there was a 3-fold increase in the cesarean delivery rate in women who were induced when compared with those who were treated expectantly at 40 completed weeks' gestation.

conclusionInduction of labor in women with mild gestational diabetes mellitus does not increase the rate of cesarean delivery at <40 weeks' gestation.

Indexed as

AdultCesarean SectionDiabetes, GestationalFemaleGestational AgeHumansLabor, InducedLogistic ModelsPregnancyRiskTime Factorscesarean deliverygestational diabetes mellitusinduction of labor

Identifiers

PMID24607755
PMCPMC4149809
OpenAlexW1986956627

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.