Evidence map›Paper›PMID 24607400›Full record

ArticleCell stem cell2014

Reprogramming can be a transforming experience.

Robin M Hobbs, Jose M Polo

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell stem cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Robin M HobbsAustralian Regenerative Medicine Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne 3800, VIC, Australia.
Jose M PoloAustralian Regenerative Medicine Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne 3800, VIC, Australia. Electronic address: jose.polo@monash.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the inception of nuclear reprogramming, the parallels between this process and tumorigenesis have become increasingly apparent. Recent studies by Abad et al. and Ohnishi et al. have now formalized this connection by demonstrating that the same transcription factors used for reprogramming to pluripotency drive tumor initiation in vivo.

Indexed as

Cellular ReprogrammingEpigenesis, GeneticGene Expression Regulation, NeoplasticAnimalsFemaleInduced Pluripotent Stem CellsKidney NeoplasmsMaleTeratomaTotipotent Stem Cells

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.