Evidence map›Paper›PMID 24607223›Full record

ReviewNeuron2014

Optic ataxia: from Balint's syndrome to the parietal reach region.

Richard A Andersen, Kristen N Andersen, Eun Jung Hwang, Markus Hauschild

Open access · bronzeAbstract readReview
In one paragraph

Review in Neuron, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  7. Article
  8. Article
  9. Article
  10. Review
  11. Unilateral Optic Ataxia of the Leg.Internal medicine (Tokyo, Japan) · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Freezing of saccades in dopa-responsive parkinsonian syndrome.American journal of ophthalmology case reports · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Richard A AndersenDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: andersen@vis.caltech.edu.
Kristen N AndersenDepartments of Neurology and Pediatrics, University of California, Los Angeles Medical Center, Los Angeles, CA 90095, USA.
Eun Jung HwangDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
Markus HauschildDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
California Institute of Technology · USLos Angeles Medical Center · USUniversity of California, San Diego · US

Funding

The Neurobiology of Social Decision-Making: Social Inference and ContextP50MH094258 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI O'DOHERTY, JOHN P · 2012 to 2021
$18.6M
Smart MEMS recording systems for visual cortical studiesR01EY015545 · NEI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANDERSEN, RICHARD A · 2005 to 2020
$9.6M
NEURAL PROSTHESIS USING POSTERIOR PARIETAL REACH REGIONR01EY013337 · NEI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANDERSEN, RICHARD A · 2001 to 2015
$6.5M
Visual/Spatial Properties of Posterior Parietal NeuronsR01EY005522 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ANDERSEN, RICHARD A · 1985 to 2011
$5.7M
VISUAL MOTION PROCESSINGR01EY007492 · NEI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ANDERSEN, RICHARD A · 1987 to 2014
$4.7M
NEI NIH HHS R01 EY005522NEI NIH HHS R01 EY007492NEI NIH HHS R01 EY013337NEI NIH HHS R01 EY015545NIMH NIH HHS P50 MH094258
6 · The paper itself

Abstract

Optic ataxia is a high-order deficit in reaching to visual goals that occurs with posterior parietal cortex (PPC) lesions. It is a component of Balint's syndrome that also includes attentional and gaze disorders. Aspects of optic ataxia are misreaching in the contralesional visual field, difficulty preshaping the hand for grasping, and an inability to correct reaches online. Recent research in nonhuman primates (NHPs) suggests that many aspects of Balint's syndrome and optic ataxia are a result of damage to specific functional modules for reaching, saccades, grasp, attention, and state estimation. The deficits from large lesions in humans are probably composite effects from damage to combinations of these functional modules. Interactions between these modules, either within posterior parietal cortex or downstream within frontal cortex, may account for more complex behaviors such as hand-eye coordination and reach-to-grasp.

Indexed as

AgnosiaAnimalsAtaxiaAttentionHumansParietal LobePsychomotor Performance

Identifiers

PMID24607223
PMCPMC4000741
OpenAlexW2000408106

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.