Evidence map›Paper›PMID 24607047›Full record

ArticleThe journal of allergy and clinical immunology. In practice

Validation of parental reports of asthma trajectory, burden, and risk by using the pediatric asthma control and communication instrument.

Sande O Okelo, Michelle N Eakin, Kristin A Riekert, Alvin P Teodoro, Andrew L Bilderback, Darcy A Thompson, Antonio Loiaza-Martinez, Cynthia S Rand, Shannon Thyne, Gregory B Diette and 1 more

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Stress and Quality of Life in Urban Caregivers of Children With Poorly Controlled Asthma: A Longitudinal Analysis.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Severe asthma in children.The journal of allergy and clinical immunology. In practice
    Review
  7. Assessment of Quality of Life of Primary Caregivers of Egyptian Asthmatic Children and Adolescents.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sande O OkeloDepartment of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, Calif. Electronic address: sokelo@mednet.ucla.edu.
Michelle N EakinDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, Md.
Kristin A RiekertDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, Md.
Alvin P TeodoroDepartment of Pediatrics, New York Presbyterian/Weill Medical College of Cornell University, New York, NY.
Andrew L BilderbackDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, Md.
Darcy A ThompsonDepartment of Pediatrics, University of Colorado, Denver, Colo.
Antonio Loiaza-MartinezDivision of Pediatric Pulmonology, Hospital Infantil de Las Californias, Tijuana, Mexico.
Cynthia S RandDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, Md.
Shannon ThyneDepartment of Pediatrics, University of California San Francisco, San Francisco, Calif.
Gregory B DietteDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, Md.
Cecilia M PatinoDepartment of Preventive Medicine, University of Southern California, Los Angeles, Calif.

Funding

Mentoring and Patient Oriented Research in AsthmaK24ES021098 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI DIETTE, GREGORY B · 2012 to 2016
$927k
Development of a Pediatric Asthma Control and Communication InstrumentK23HL089410 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OKELO, SANDE O · 2008 to 2012
$715k
Parenting regarding TV viewing and overweight in Latino preschool childrenK23HD060666 · NICHD · UNIVERSITY OF COLORADO DENVER · PI THOMPSON, DARCY ANN · 2009 to 2013
$672k
NHLBI NIH HHS HL089410NHLBI NIH HHS K23 HL089410NICHD NIH HHS K23 HD060666NIEHS NIH HHS K24 ES021098
6 · The paper itself

Abstract

backgroundDespite a growing interest, few pediatric asthma questionnaires assess multiple dimensions of asthma morbidity, as recommended by national asthma guidelines, or use patient-reported outcomes.

objectiveTo evaluate a questionnaire that measures multiple dimensions of parent-reported asthma morbidity (Direction, Bother, and Risk).

methodsWe administered the Pediatric Asthma Control and Communication Instrument (PACCI) and assessed asthma control (PACCI Control), quality of life, and lung function among children who presented for routine asthma care. The PACCI was evaluated for discriminative validity.

resultsA total of 317 children participated (mean age, 8.2 years; 58% boys; 44% African American). As parent-reported PACCI Direction changed from "better" to "worse," we observed poorer asthma control (P < .001), mean Pediatric Asthma Caregiver Quality of Life Questionnaire (PACQLQ) scores (P < .001), and FEV1% (P = .025). Linear regression showed that, for each change in PACCI Direction, the mean PACQLQ score decreased by -0.6 (95% CI, -0.8 to -0.4). As parent-reported PACCI Bother changed from "not bothered" to "very bothered," we observed poorer asthma control (P < .001) and lower mean PACQLQ scores (P < .001). Linear regression showed that, for each change in PACCI Bother category, the mean PACQLQ score decreased by -1.1 (95% CI, -1.3 to -0.9). Any reported PACCI Risk event (emergency department visit, hospitalization, or use of an oral corticosteroid) was associated with poorer asthma control (P < .05) and PACQLQ scores (P < .01).

conclusionsPACCI Direction, Bother, and Risk are valid measures of parent-reported outcomes and show good discriminative validity. The PACCI is a simple clinical tool to assess multiple dimensions of parent-reported asthma morbidity, in addition to risk and control.

Indexed as

AdolescentAdultAsthmaChildChild, PreschoolCommunicationCost of IllnessCross-Sectional StudiesFemaleForced Expiratory VolumeHumansInfantMaleParentsQuality of LifeRisk FactorsBurdenChildrenPACCIPatient-reported outcomesRiskSurveyTrajectoryValidation

Identifiers

PMID24607047
PMCPMC4361408

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.