ArticleDeutsches Arzteblatt international2014
Antipsychotic prescription in children and adolescents: an analysis of data from a German statutory health insurance company from 2005 to 2012.
Article in Deutsches Arzteblatt international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Prescription prevalence of psychotropic drugs in children and adolescents: an analysis of international data.European journal of clinical pharmacology · 2019Pooled it
- Atypical antipsychotics for disruptive behaviour disorders in children and youths.The Cochrane database of systematic reviews · 2017Pooled it
- Trends in Atypical Antipsychotic Use Among Children and Adolescents With Depressive Disorders in Korea.Journal of Korean medical science · 2026Article
- Predictors of extrapyramidal side effects among patients taking antipsychotic medication at Mekelle psychiatry units, Northern Ethiopia, 2023: unmatched case-control study.BMC psychiatry · 2025Article
- Sex-Specific Differences in Antidepressant and Antipsychotic Treatment Outcomes and Serum Levels in Children and Adolescents.Pharmaceutics · 2025Article
- Early-life risperidone alters locomotor responses to apomorphine and quinpirole in adulthood.Behavioural brain research · 2024Article
- Retrospective Study on the Therapeutic Effect of Repetitive Transcranial Magnetic Stimulation Combined with Tiapride Hydrochloride Tablets in Children with Attention Deficit Hyperactivity Disorder.Alpha psychiatry · 2024Article
- Antipsychotic prescribing patterns in children and adolescents attending Australian general practice in 2011 and 2017.JCPP advances · 2024Article
- Recognition and management of children and adolescents with conduct disorder: a real-world data study from four western countries.Child and adolescent psychiatry and mental health · 2024Article
- Trends in Prescribing Antipsychotics for Children and Adolescents in Japan: A Descriptive Epidemiological Study Using a Large-Scale Pharmacy Dataset.Child psychiatry and human development · 2023Article
- Use of atypical antipsychotics in the treatment of schizophrenia in the Brazilian National Health System: a cohort study, 2008-2017.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2023Article
- Value of a web-based pediatric drug information system to prevent serious adverse drug reactions in child and adolescent psychiatry.Journal of neural transmission (Vienna, Austria : 1996) · 2023Article
- Trends in antipsychotic use among children and adolescents in Germany: a study using 2011-2020 nationwide outpatient claims data.Frontiers in psychiatry · 2023Article
- Gender differences in the use of atypical antipsychotics in early-onset schizophrenia: a nationwide population-based study in Brazil.BMC psychiatry · 2021Article
- Risk of seizures associated with antipsychotic treatment in pediatrics with psychiatric disorders: a nested case-control study in Korea.European child & adolescent psychiatry · 2021Article
- Estimation of a preliminary therapeutic reference range for children and adolescents with tic disorders treated with tiapride.European journal of clinical pharmacology · 2021Observational
- The Burden of Antipsychotic-Induced Weight Gain and Metabolic Syndrome in Children.Frontiers in psychiatry · 2021Review
- Safety and Tolerability of Antipsychotic Drugs in Pediatric Patients: Data From a 1-Year Naturalistic Study.Frontiers in psychiatry · 2020Article
- New Users of Antipsychotics Among Children and Adolescents in 2008-2017: A Nationwide Register Study.Frontiers in psychiatry · 2020Article
- Prescriptions for Alpha Agonists and Antipsychotics in Children and Youth with Tic Disorders: A Pharmacoepidemiologic Study.Tremor and other hyperkinetic movements (New York, N.Y.) · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite sparse documentation of their long-term therapeutic effects and side effects, antipsychotic drugs have come to be prescribed more frequently for children and adolescents in recent years, both in the USA and in Europe. No current data are available about antipsychotic prescriptions for this age group in Germany.
methodsData from the largest statutory health insurance fund in Germany (BARMER GEK) were studied to identify antipsychotic prescriptions for children and adolescents (age 0-19 years) from 2005 to 2012 and analyze them with respect to age, sex, drug prescribed, prescribing medical specialty, and any observable secular trends.
resultsThe percentage of children and adolescents receiving a prescription for an antipsychotic drug rose from 0.23% in 2005 to 0.32% in 2012. In particular, atypical antipsychotic drugs were prescribed more frequently over time (from 0.10% in 2005 to 0.24% in 2012). The rise in antipsychotic prescriptions was particularly marked among 10- to 14-year-olds (from 0.24% to 0.43%) and among 15- to 19-year-olds (from 0.34% to 0.54%). The prescribing physicians were mostly either child and adolescent psychiatrists or pediatricians; the most commonly prescribed drugs were risperidone and pipamperone. Risperidone was most commonly prescribed for patients with hyperkinetic disorders and conduct disorders.
conclusionIn Germany as in other industrialized countries, antipsychotic drugs have come to be prescribed more frequently for children and adolescents in ecent years. The German figures, while still lower than those from North America, are in the middle range of figures from European countries. The causes of the increase should be critically examined; if appropriate, the introduction of prescribing guidelines of a more restrictive nature could be considered.
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