Evidence map›Paper›PMID 24606556›Full record

ReviewExpert review of vaccines2014

Identifying vaccine targets for anti-leishmanial vaccine development.

Shyam Sundar, Bhawana Singh

Abstract readReview
In one paragraph

Review in Expert review of vaccines, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
  2. Immunization withVaccines · 2024
    Article
  3. Review
  4. Article
  5. Current leishmaniasis drug discovery.RSC medicinal chemistry · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Vaccination in Leishmaniasis: A Review Article.Iranian biomedical journal · 2022
    Article
  10. Proteomic Analysis ofPathogens (Basel, Switzerland) · 2021
    Article
  11. Targeted Deletion of Centrin inFrontiers in cellular and infection microbiology · 2021
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Analysis of the Antigenic and Prophylactic Properties of theFrontiers in cellular and infection microbiology · 2018
    Article
  18. Article
  19. Article
  20. Lipophosphoglycan 3 FromBioinformatics and biology insights · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shyam Sundar
Bhawana Singh

Funding

Visceral Leishmaniasis in Bihar State, IndiaP50AI074321 · NIAID · BANARAS HINDU UNIVERSITY · PI SUNDAR, SHYAM · 2007 to 2016
$6.4M
Visceral Leishmaniasis in Bihar State, IndiaU19AI074321 · NIAID · BANARAS HINDU UNIVERSITY · PI SUNDAR, SHYAM · 2017 to 2021
$2.8M
NIAID NIH HHS P50 AI074321NIAID NIH HHS P50AI074321NIAID NIH HHS U19 AI074321
6 · The paper itself

Abstract

Leishmaniasis is a neglected tropical disease spread by an arthropod vector. It remains a significant health problem with an incidence of 0.2–0.4 million visceral leishmaniasis and 0.7–1.2 million cutaneous leishmaniasis cases each year. There are limitations associated with the current therapeutic regimens for leishmaniasis and the fact that after recovery from infection the host becomes immune to subsequent infection therefore, these factors force the feasibility of a vaccine for leishmaniasis. Publication of the genome sequence of Leishmania has paved a new way to understand the pathogenesis and host immunological status therefore providing a deep insight in the field of vaccine research. This review is an effort to study the antigenic targets in Leishmania to develop an anti-leishmanial vaccine.

Indexed as

Antigens, ProtozoanDrug DiscoveryGenome, ProtozoanHumansLeishmaniaLeishmaniasisLeishmaniasis VaccinesAntigens, ProtozoanLeishmaniasis Vaccines

Identifiers

PMID24606556
PMCPMC4040457

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.