Evidence map›Paper›PMID 24605215›Full record

ArticleBoneKEy reports2014

Vitamin D and chronic kidney disease-mineral bone disease (CKD-MBD).

Sagar U Nigwekar, Hector Tamez, Ravi I Thadhani

Open access · greenAbstract read
In one paragraph

Article in BoneKEy reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 108 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Mechanisms underlying atrial fibrillation in chronic kidney disease.Journal of molecular and cellular cardiology · 2025
    Review
  6. Article
  7. Article
  8. bioRxiv : the preprint server for biology · 2024
    Article
  9. Vitamin D: A Bridge between Kidney and Heart.Life (Basel, Switzerland) · 2024
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Regulation of 1 and 24 hydroxylation of vitamin D metabolites in the proximal tubule.Experimental biology and medicine (Maywood, N.J.) · 2022
    Review
  15. miRNA biomarkers in renal disease.International urology and nephrology · 2022
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sagar U NigwekarDivision of Nephrology, Massachusetts General Hospital , Boston, MA, USA.
Hector TamezDivision of Cardiology, Beth Israel Deaconess Medical Center , Boston, MA, USA.
Ravi I ThadhaniDivision of Nephrology, Massachusetts General Hospital , Boston, MA, USA.
Massachusetts General Hospital · USBeth Israel Deaconess Medical Center · US

Funding

Redefining Vitamin D Deficiency: The Role of Bioavailable Vitamin DR01DK094486 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI KARUMANCHI, S. ANANTH, THADHANI, RAVI · 2012 to 2018
$2.9M
Patient Oriented Studies of Vitamin D in Chronic Kidney DiseaseK24DK094872 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI THADHANI, RAVI · 2012 to 2016
$546k
NIDDK NIH HHS K24 DK094872NIDDK NIH HHS R01 DK094486
6 · The paper itself

Abstract

Chronic kidney disease (CKD) is a modern day epidemic and has significant morbidity and mortality implications. Mineral and bone disorders are common in CKD and are now collectively referred to as CKD- mineral and bone disorder (MBD). These abnormalities begin to appear even in early stages of CKD and contribute to the pathogenesis of renal osteodystrophy. Alteration in vitamin D metabolism is one of the key features of CKD-MBD that has major clinical and research implications. This review focuses on biology, epidemiology and management aspects of these alterations in vitamin D metabolism as they relate to skeletal aspects of CKD-MBD in adult humans.

Identifiers

PMID24605215
PMCPMC3944129
OpenAlexW2061836935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.