ArticleFrontiers in aging neuroscience2014
Clinical, physical and lifestyle variables and relationship with cognition and mood in aging: a cross-sectional analysis of distinct educational groups.
Article in Frontiers in aging neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Magnetic resonance elastography of the ageing brain in normal and demented populations: A systematic review.Human brain mapping · 2022Pooled it
- Connecting the dots on health inequalities--a systematic review on the social determinants of health in Portugal.International journal for equity in health · 2016Pooled it
- The Bounds Of Education In The Human Brain Connectome.Scientific reports · 2015Trial
- Article
- The Association Between Cognitive Functioning and Depression Severity: A Multiwave Longitudinal Remote Assessment Study.Depression and anxiety · 2025Article
- Reliability and validity of the Brief Attention and Mood Scale of 7 Items: a self-administered, online assessment.Frontiers in psychology · 2025Article
- Association between Depressive Mood, Antidepressant Therapy and Neuropsychological Performances: Results from a Cross-Sectional Study on Elderly Patients.Brain sciences · 2024Article
- The association between persistent cognitive difficulties and depression and functional outcomes in people with major depressive disorder.Psychological medicine · 2023Observational
- Poor Cognitive Agility Conservation in Obese Aging People.Biomedicines · 2023Article
- The aging mind: A complex challenge for research and practice.Aging brain · 2023Review
- A novel method for estimating connectivity-based parcellation of the human brain from diffusion MRI: Application to an aging cohort.Human brain mapping · 2022Article
- The longitudinal impact of the COVID-19 pandemic on health behaviors, psychosocial factors, and cognitive functioning in older adults.Frontiers in aging neuroscience · 2022Article
- Optimized Multiscale Entropy Model Based on Resting-State fMRI for Appraising Cognitive Performance in Healthy Elderly.Computational and mathematical methods in medicine · 2022Article
- Evaluation of the genetic risk for COVID-19 outcomes in COPD and differences among worldwide populations.PloS one · 2022Article
- Reorganization of brain structural networks in aging: A longitudinal study.Journal of neuroscience research · 2021Article
- Signatures of white-matter microstructure degradation during aging and its association with cognitive status.Scientific reports · 2021Article
- The Association of Metabolic Dysfunction and Mood Across Lifespan Interacts With the Default Mode Network Functional Connectivity.Frontiers in aging neuroscience · 2021Article
- Association of positive and negative life events with cognitive performance and psychological status in late life: A cross-sectional study in Northern Portugal.Aging brain · 2021Article
- Iron Status is Associated with Mood, Cognition, and Functional Ability in Older Adults: A Cross-Sectional Study.Nutrients · 2020Article
- Neurocognitive impairment in type 2 diabetes: evidence for shared genetic aetiology.Diabetologia · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is relevant to unravel the factors that may mediate the cognitive decline observed during aging. Previous reports indicate that education has a positive influence on cognitive performance, while age, female gender and, especially, depressed mood were associated with poorer performances across multiple cognitive dimensions (memory and general executive function). Herein, the present study aimed to characterize the cognitive performance of community-dwelling individuals within distinct educational groups categorized by the number of completed formal school years: "less than 4," "4, completed primary education," and "more than 4." Participants (n = 1051) were randomly selected from local health registries and representative of the Portuguese population for age and gender. Neurocognitive and clinical assessments were conducted in local health care centers. Structural equation modeling was used to derive a cognitive score, and hierarchical linear regressions were conducted for each educational group. Education, age and depressed mood were significant variables in directly explaining the obtained cognitive score, while gender was found to be an indirect variable. In all educational groups, mood was the most significant factor with effect on cognitive performance. Specifically, a depressed mood led to lower cognitive performance. The clinical disease indices cardiac and stroke associated with a more negative mood, while moderate increases in BMI, alcohol consumption and physical activity associated positively with improved mood and thus benefitted cognitive performance. Results warrant further research on the cause-effect (longitudinal) relationship between clinical indices of disease and risk factors and mood and cognition throughout aging.
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