Evidence map›Paper›PMID 24605090›Full record

ReviewFrontiers in systems neuroscience2014

Not all brains are created equal: the relevance of individual differences in responsiveness to transcranial electrical stimulation.

Beatrix Krause, Roi Cohen Kadosh

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in systems neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
165citing papers in PubMed, 4 pooled it
18.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

165 citing papers in PubMed, 4 syntheses or guidelines pooled it, 334 citations in OpenAlex.

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  16. The efficacy of transcranial random noise stimulation (tRNS) on mood may depend on individual differences including age and trait mood.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2018
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  18. Functional role of frontal alpha oscillations in creativity.Cortex; a journal devoted to the study of the nervous system and behavior · 2015
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105 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Beatrix KrauseDepartment of Experimental Psychology, University of Oxford Oxford, UK.
Roi Cohen KadoshDepartment of Experimental Psychology, University of Oxford Oxford, UK.
University of Oxford · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

A current issue in the research of augmentation of brain functions using transcranial electrical stimulation (tES) is the diversity and inconsistency in outcome results. Similar studies often report different results, depending on the parameters and tasks used. Such inconsistencies have led to significant doubts about the efficacy of the method in the broader scientific community, despite its promising potential for patient recovery and treatment. Evidence on the large variability in individual cortical excitability and response to tES suggests that stimulation may affect individuals differently, depending on the subject's age, gender, brain state, hormonal levels, and pre-existing regional excitability. Certain factors might even lead to the reversal of polarity-dependent effects, and therefore have crucial implications for neurorehabilitation and cognitive enhancement. Research paradigms may have to be refined in the future to avoid the confounding effects of such factors.

Indexed as

efficacyexcitationindividualinhibitionresponsivetranscranial electrical stimulation

Identifiers

PMID24605090
PMCPMC3932631
OpenAlexW2115679772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.