ArticleJournal of experimental botany2014
Conserved miR164-targeted NAC genes negatively regulate drought resistance in rice.
Article in Journal of experimental botany, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 179 papers, 3 of them syntheses that pooled it.
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Who cites it
179 citing papers in PubMed, 3 syntheses or guidelines pooled it, 384 citations in OpenAlex.
- Genome-wide association study to identify genomic loci associated with early vigor in bread wheat under simulated water deficit complemented with quantitative trait loci meta-analysis.G3 (Bethesda, Md.) · 2023Pooled it
- Pooled it
- Genome-wide analysis, expansion and expression of the NAC family under drought and heat stresses in bread wheat (T. aestivum L.).PloS one · 2019Pooled it
- LpCbDR1 regulates leaf senescence and drought tolerance by activating the chlorophyll b reductase gene and stress-related genes in perennial ryegrass.Horticulture research · 2026Article
- Molecular Crosstalk Between Flowering Time and Drought Adaptation in Cereal Crops.Plants (Basel, Switzerland) · 2026Review
- Phytohormonal and Transcriptomic Mechanisms of Multigenerational Stress Memory in Wheat Under Weed Competition.Plant, cell & environment · 2026Article
- FAD-Linked Oxidoreductase Protein 1 (FLO1) Coordinates Grain Development and Drought Tolerance in Rice.Plants (Basel, Switzerland) · 2026Article
- MicroRNA networks in rice seeds: unveiling key regulators of development, germination, and rice resilience under climate changes.Journal of experimental botany · 2026Review
- The miR164b-SiNAC015 Module Regulates Drought Tolerance by Scavenging Reactive Oxygen Species in Foxtail Millet.Plant biotechnology journal · 2026Article
- The miR164e-NAC32 module orchestrates maize plant height via post-translational regulation of DELLA protein stability.Plant communications · 2026Article
- ComparativeFrontiers in plant science · 2026Article
- Rice and shine: a review of miRNA-mediated responses to abiotic stress inFrontiers in plant science · 2026Review
- Article
- MicroRNA164d suppresses the HvNAC92-HvHKT1;5 module to enhance salinity tolerance in barley.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- ThePlants (Basel, Switzerland) · 2025Article
- Comprehensive Identification of Key Genes Responsible for Leaf Senescence of Rice (Plants (Basel, Switzerland) · 2025Article
- Non-coding RNAs in plant stress responses: molecular insights and agricultural applications.Plant biotechnology journal · 2025Review
- Comprehensive genome-wide characterization of NAC transcription factors in Barley influence insights into stress tolerance and evolutionary dynamics.Scientific reports · 2025Article
- TheInternational journal of molecular sciences · 2025Article
- Phenomics-assisted genetic dissection and molecular design of drought resistance in rice.Plant communications · 2025Article
119 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs constitute a large group of endogenous small RNAs of ~22 nt that emerge as vital regulators, mainly by targeting mRNAs for post-transcriptional repression. Previous studies have revealed that the miR164 family in Arabidopsis is comprised of three members which guide the cleavage of the mRNAs of five NAC genes to modulate developmental processes. However, the functions of the miR164-targeted NAC genes in crops are poorly deciphered. In this study, the conserved features of six miR164-targeted NAC genes (OMTN1-OMTN6) in rice are described, and evidence is provided that four of them confer a negative regulatory role in drought resistance. OMTN proteins have the characteristics of typical NAC transcriptional factors. The miR164 recognition sites of the OMTN genes are highly conserved in rice germplasms. Deletion of the recognition sites impaired the transactivation activity, indicating that the conserved recognition sites play a crucial role in maintaining the function of the OMTN proteins. The OMTN genes were responsive to abiotic stresses, and showed diverse spatio-temporal expression patterns in rice. Overexpression of OMTN2, OMTN3, OMTN4, and OMTN6 in rice led to negative effects on drought resistance at the reproductive stage. The expression of numerous genes related to stress response, development, and metabolism was altered in OMTN2-, OMTN3-, OMTN4-, and OMTN6-overexpressing plants. Most of the up-regulated genes in the OMTN-overexpressing plants were down-regulated by drought stress. The results suggest that the conserved miR164-targeted NAC genes may be negative regulators of drought tolerance in rice, in addition to their reported roles in development.
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