Evidence map›Paper›PMID 24604560›Full record

ArticleHuman psychopharmacology2014

Positive perception of pharmacogenetic testing for psychotropic medications.

Matthew B Lanktree, Gwyneth Zai, Laura E Vanderbeek, Daniel E Giuffra, David S Smithson, Lucas B Kipp, Timothy R Dalseg, Mark Speechley, James L Kennedy

Abstract read
In one paragraph

Article in Human psychopharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Pharmacogenetics and outcome with antipsychotic drugs.Dialogues in clinical neuroscience · 2014
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matthew B LanktreeDepartment of Medicine, School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada; Department of Biochemistry, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada.
Gwyneth Zai
Laura E Vanderbeek
Daniel E Giuffra
David S Smithson
Lucas B Kipp
Timothy R Dalseg
Mark Speechley
James L Kennedy

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPharmacogenetics attempts to identify inter-individual genetic differences that are predictive of variable drug response and propensity to side effects, with the prospect of assisting physicians to select the most appropriate drug and dosage for treatment. However, many concerns regarding genetic tests exist. We sought to test the opinions of undergraduate science and medical students in southern Ontario universities toward pharmacogenetic testing. METHODS AND

resultsQuestionnaires were completed by 910 undergraduate medicine and science students from 2005 to 2007. Despite students' concerns that the results of genetic tests may be used for other purposes without consent (71%) or lead to discrimination (78%), an overwhelming number of students were in favor of pharmacogenetic testing (90%). DISCUSSION: To our knowledge, this study is the first to survey a large sample for their attitude toward pharmacogenetic testing for psychotropic medications. Our results indicate that, although concerns remain and scientific advancements are required, respondents were in support of pharmacogenetic testing for medications used to treat schizophrenia. © 2014 The Authors. Human Psychopharmacology: Clinical and Experimental published by John Wiley & Sons, Ltd.

Indexed as

Genetic TestingHealth Knowledge, Attitudes, PracticePharmacogeneticsAdolescentAdultCanadaFemaleHumansInformed ConsentMalePrejudicePsychotropic DrugsSchizophreniaStudentsSurveys and QuestionnairesUniversitiesPsychotropic Drugsantipsychoticsbioethicsgeneticspharmacogeneticspsychopharmacology

Identifiers

PMID24604560
PMCPMC4237188

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.