ReviewDigestive diseases (Basel, Switzerland)2014
Unmet therapeutic needs in eosinophilic esophagitis.
Review in Digestive diseases (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- AlEuropean journal of nuclear medicine and molecular imaging · 2026Article
- A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
- Evaluation of long-term course in children with eosinophilic esophagitis reveals distinct histologic patterns and clinical characteristics.The Journal of allergy and clinical immunology · 2019Article
- The New Paradigms in Clinical Research: From Early Access Programs to the Novel Therapeutic Approaches for Unmet Medical Needs.Frontiers in pharmacology · 2019Review
- Systematic review of histological remission criteria in eosinophilic esophagitis.JGH open : an open access journal of gastroenterology and hepatology · 2018Review
- Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites.The Journal of allergy and clinical immunology · 2018Observational
- New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting.The Journal of allergy and clinical immunology · 2018Article
- Pathophysiology of Eosinophilic Esophagitis.Gastroenterology · 2018Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Eosinophilic esophagitis (EoE) is a clinicopathologic disease of increasing prevalence in children and adults worldwide. EoE is defined by a robust, acid-resistant, often panesophageal eosinophilia. Disease complications include food impactions and strictures. While much has been learned since it was first described in the late 1970s, there are still a number of unmet clinical needs. This review provides an overview of these and addresses our current state of progress in meeting these challenges. The best diagnostic criteria, the least invasive mechanisms for procuring tissue, the best therapeutic intervention, and an understanding of how therapies affect EoE natural history remain to be systematically addressed. In addition, the classification of EoE subjects by phenotype, genotype, and/or endotype is required but dependent upon further large-scale systematic studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.