ArticleBritish dental journal2014
Identifying adults at risk of paracetamol toxicity in the acute dental setting: development of a clinical algorithm.
Article in British dental journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Analgesic Overdose in Patients With Dental Pain. A Cross-Sectional Study in Two Dental Emergency Clinics.Basic & clinical pharmacology & toxicology · 2025Article
- Association of Gender, Painkiller Use, and Experienced Pain with Pain-Related Fear and Anxiety among University Students According to the Fear of Pain Questionnaire-9.International journal of environmental research and public health · 2021Article
- Dental pain management - a cause of significant morbidity due to paracetamol overdose.British dental journal · 2018Article
- Analgesia (mis)usage on a dental emergency service: a patient survey.Clinical oral investigations · 2018Article
- Paracetamol overdose secondary to dental pain: a case series.British dental journal · 2015Article
- Summary of: Paracetamol overdose secondary to dental pain: a case series.British dental journal · 2015Article
- Pharmacology: inflammatory definitions.British dental journal · 2014Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paracetamol is widely used and effective for the management of dental pain in the UK. Acute dental pain is a recognised precipitant of unintentional paracetamol overdose and in a small but significant number of cases this results in hepatotoxicity. Patients' understanding of the risks of excess paracetamol ingestion remains poor and risk of over-medication before presentation is increased due to a variety of factors including dental anxiety and fragmented provision of dental emergency services. Early recognition of overdose is crucial to preventing significant hepatotoxicity and death. Dentists have a role to play in recognising unintentional overdose cases and directing patients timeously to appropriate medical care. Guidelines on the treatment of paracetamol toxicity are readily available but our data suggests some dental settings may present a weak link in the care pathway and overdose may not be readily recognised. We have developed an algorithm and training package targeted at dentists in the acute dental setting with the aim of improving recognition of paracetamol toxicity in adults and directing onward referral appropriately. This paper also revises the key pharmacokinetics and pharmacodynamics of paracetamol and is intended to raise awareness of issues of toxicity for dentists.
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Registered trials
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