Evidence map›Paper›PMID 24603165›Full record

ReviewNature reviews. Immunology2014

Leukocyte migration in the interstitial space of non-lymphoid organs.

Wolfgang Weninger, Maté Biro, Rohit Jain

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 209 citations in OpenAlex.

  1. Article
  2. Article
  3. Chemical and Mechanical Regulation of Leukocyte Migration.Cold Spring Harbor perspectives in biology · 2026
    Review
  4. Article
  5. Statistical and mechanical analysis of multi-pseudopodial locomotion in a testate amoeba, Arcella sp.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. NF-κB in inflammation and cancer.Cellular & molecular immunology · 2025
    Review
  11. Article
  12. Review
  13. Bile acids and their receptors in hepatic immunity.Liver research (Beijing, China) · 2025
    Review
  14. Article
  15. CaNature communications · 2024
    Article
  16. Article
  17. Article
  18. Innate Immune Training Initiates Efferocytosis to Protect against Lung Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  19. Article
  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wolfgang Weninger1] Centenary Institute for Cancer Medicine and Cell Biology, Newtown, New South Wales 2042, Australia. [2] Discipline of Dermatology, University of Sydney, New South Wales 2006, Australia. [3] Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Australia.
Maté Biro1] Centenary Institute for Cancer Medicine and Cell Biology, Newtown, New South Wales 2042, Australia. [2] Sydney Medical School, The University of Sydney, New South Wales 2006, Australia.
Rohit JainCentenary Institute for Cancer Medicine and Cell Biology, Newtown, New South Wales 2042, Australia.
Centenary Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukocyte migration through interstitial tissues is essential for mounting a successful immune response. Interstitial motility is governed by a vast array of cell-intrinsic and cell-extrinsic factors that together ensure the proper positioning of immune cells in the context of specific microenvironments. Recent advances in imaging modalities, in particular intravital confocal and multi-photon microscopy, have helped to expand our understanding of the cellular and molecular mechanisms that underlie leukocyte navigation in the extravascular space. In this Review, we discuss the key factors that regulate leukocyte motility within three-dimensional environments, with a focus on neutrophils and T cells in non-lymphoid organs.

Indexed as

AnimalsCell MovementCellular MicroenvironmentChemotaxis, LeukocyteExtracellular FluidHumansLeukocytesModels, BiologicalNeutrophilsOrgan SpecificityT-LymphocytesTumor Microenvironment

Identifiers

PMID24603165
OpenAlexW2000513178

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.