Evidence map›Paper›PMID 24603005›Full record

ArticleClinical trials (London, England)2014

Increasing Asian American participation in clinical trials by addressing community concerns.

Grace X Ma, Brenda Seals, Yin Tan, Sylvia Y Wang, Richard Lee, Carolyn Y Fang

Abstract read
In one paragraph

Article in Clinical trials (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Grace X Maa Center for Asian Health, College of Health Professions, Temple University, Philadelphia, PA, USA.
Brenda Sealsa Center for Asian Health, College of Health Professions, Temple University, Philadelphia, PA, USA.
Yin Tana Center for Asian Health, College of Health Professions, Temple University, Philadelphia, PA, USA.
Sylvia Y Wanga Center for Asian Health, College of Health Professions, Temple University, Philadelphia, PA, USA.
Richard Leec Asian Community Health Coalition, Philadelphia, PA, USA.
Carolyn Y Fangd Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
Temple University · USAsian Health Coalition · USFox Chase Cancer Center · US

Funding

Training ProgramU54CA153513 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI MA, GRACE X. · 2010 to 2015
$5.2M
NCI NIH HHS U54 CA153513
6 · The paper itself

Abstract

Background Asian Americans are underrepresented in clinical trials, but little is known about the factors that contribute to clinical trial participation in this population. Purpose The purpose of this study was to identify knowledge, barriers, facilitators, and cultural influences on participating in clinical trials among three Asian American ethnic groups. Concurrently, we sought to identify mechanisms and messages to facilitate dissemination of information and to identify strategies to promote clinical trial participation in this population. Methods Eight focus groups were conducted (n = 103) with Chinese (four groups), Korean (two groups), and Vietnamese (two groups) Americans. Each group was conducted with a moderator and a translator using a standardized guide. Results Participants discuss the benefits of contributing to science, future generations, and their families by being in clinical trials. Some participants think clinical trials would give hope to those with terminal illnesses. A doctor's recommendation, being sick, and needing more options for treatment are motivators for Asian Americans. Having some guarantee of treatment effectiveness and lack of side effects facilitates participation. Cultural or religious beliefs are not believed to prevent clinical trial participation. Limitations This qualitative, two-site study included three Asian American ethnic groups and is not meant to establish prevalence of beliefs. Conclusion Asian Americans need more information about clinical trials and their benefits to science and the larger community. Health-care providers can play pivotal roles in enhancing recruitment of Asian Americans. Basing recruitment goals on percentage representation in most US geographic areas does not provide sufficient numbers to allow for analysis of minorities like Asian American groups. The discovery of important group-specific harms and benefits depends on greater participation of racial/ethnic subgroups.

Indexed as

Community ParticipationHealth Knowledge, Attitudes, PracticeAdultAgedAsianClinical Trials as TopicFemaleFocus GroupsHumansMaleMiddle AgedQualitative Research

Identifiers

PMID24603005
PMCPMC4156927
OpenAlexW2121283384

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.