ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2014
Birth weight, gestational age, fetal growth and childhood asthma hospitalization.
Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 65 citations in OpenAlex.
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- Atopic diseases in pediatric population: prematurity and small for gestational age.BMC pediatrics · 2025Article
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- The influence of early life exposures on the infant gut virome.Gut microbes · 2025Article
- Simplifying Asthma: Understanding and managing asthma in young children in primary care.Pakistan journal of medical sciences · 2025Article
- Occupational psychosocial stressors and ergonomic strain during pregnancy and sex-specific risk of childhood asthma.International archives of occupational and environmental health · 2025Article
- Gestational age at birth and type 1 diabetes in childhood and young adulthood: a nationwide register study in Finland, Norway and Sweden.Diabetologia · 2024Article
- Article
- Paternal and maternal psychiatric history and risk of preterm and early term birth: A nationwide study using Swedish registers.PLoS medicine · 2023Article
- Prevalence of asthma in preterm and associated risk factors based on prescription data from the Korean National Health Insurance database.Scientific reports · 2023Article
- What is the impact of birth weight corrected for gestational age on later onset asthma: a meta-analysis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2022Review
- Gestational Age, Parent Education, and Education in Adulthood.Pediatrics · 2022Article
- Non-linear association of birth weight with lung function and risk of asthma: A population-based study.Frontiers in public health · 2022Article
- Inadequate Gestational Weight Gain and Exposure to Second-Hand Smoke during Pregnancy Increase the Risk of Low Birth Weight: A Cross-Sectional Study among Full-Term Infants.International journal of environmental research and public health · 2021Article
- Mortality Among Young Adults Born Preterm and Early Term in 4 Nordic Nations.JAMA network open · 2021Article
- Patterns of respiratory health services utilization from birth to 5 years of children who experienced adverse birth outcomes.PloS one · 2021Article
- Eight practices for data management to enable team data science.Journal of clinical and translational science · 2020Article
- Respiratory morbidity, atopy and asthma at school age in preterm infants aged 32-35 weeks.European journal of pediatrics · 2019Observational
- Birth weight is not causally associated with adult asthma: results from instrumental variable analyses.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 5 countries.
Funding
Abstract
backgroundChildhood asthma may have a fetal origin through fetal growth and development of the immunocompetence or respiratory organs.
objectiveWe examined to which extent short gestational age, low birth weight and fetal growth restriction were associated with an increased risk of asthma hospitalization in childhood.
methodsWe undertook a cohort study based on several national registers in Denmark, Sweden and Finland. We included all live singleton born children in Denmark during 1979-2005 (N = 1,538,093), in Sweden during 1973-2004 (N = 3,067,670), and a 90% random sample of singleton children born in Finland during 1987-2004 (N = 1,050,744). The children were followed from three years of age to first hospitalization for asthma, emigration, death, their 18th birthday, or the end of study (the end of 2008 in Denmark, and the end of 2007 in Sweden or Finland), whichever came first. We computed the pseudo-values for each observation and used them in a generalized estimating equation to estimate relative risks (RR) for asthma hospitalization.
resultsA total of 131,783 children were hospitalized for asthma during follow-up. The risk for asthma hospitalization consistently increased with lower birth weight and shorter gestational age. A 1000-g decrease in birth weight corresponded to a RR of 1.17 (95% confidence interval (CI) 1.15-1.18). A one-week decrease in gestational age corresponded to a RR of 1.05 (95% CI 1.04-1.06). Small for gestational age was associated with an increased risk of asthma hospitalization in term but not in preterm born children.
conclusionsFetal growth and gestational age may play a direct or indirect causal role in the development of childhood asthma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.