Evidence map›Paper›PMID 24602145›Full record

ArticleClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2014

Role of Burkholderia pseudomallei biofilm formation and lipopolysaccharide in relapse of melioidosis.

D Limmathurotsakul, A Paeyao, S Wongratanacheewin, N Saiprom, N Takpho, J Thaipadungpanit, N Chantratita, V Wuthiekanun, N P J Day, S J Peacock

Open access · hybridAbstract read
In one paragraph

Article in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Biofilm Signaling, Composition and Regulation inJournal of microbiology and biotechnology · 2023
    Review
  8. Article
  9. Review
  10. Article
  11. Frontiers in immunology · 2022
    Article
  12. Article
  13. Article
  14. An Evolutionary Arms Race BetweenFrontiers in microbiology · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Pan-drug-resistant and biofilm-producing strain ofInternational medical case reports journal · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

D LimmathurotsakulDepartment of Tropical Hygiene, Mahidol University, Bangkok, Thailand; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
A Paeyao
S Wongratanacheewin
N Saiprom
N Takpho
J Thaipadungpanit
N Chantratita
V Wuthiekanun
N P J Day
S J Peacock
Mahidol University · THMahidol Oxford Tropical Medicine Research Unit · THKhon Kaen University · TH

Funding

Wellcome Trust 090219/Z/09/Z
6 · The paper itself

Abstract

We examined whether quantitative biofilm formation and/or lipopolysaccharide type of Burkholderia pseudomallei was associated with relapsing melioidosis. We devised a 1:4 nested case-control study in which both cases and controls were drawn from a cohort of patients with primary melioidosis. Paired isolates from 80 patients with relapse and single isolates from 184 patients without relapse were tested. Relapse was associated with biofilm formation of the primary infecting isolate (conditional OR 2.03; 95% CI 1.27-3.25; p 0.003), but not with lipopolysaccharide type (p 0.74). This finding highlights the importance of biofilm formation in relapsing melioidosis.

Indexed as

AdultBiofilmsBurkholderia pseudomalleiCase-Control StudiesFemaleHumansLipopolysaccharidesMaleMelioidosisMiddle AgedRecurrenceLipopolysaccharidesBiofilmlipopolysaccharidemelioidosispseudomalleirelapse

Identifiers

PMID24602145
PMCPMC4304327
OpenAlexW2115431876

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.