ArticleInternational journal of applied & basic medical research2014
Effect of preeclampsia on insulin sensitivity.
Article in International journal of applied & basic medical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 10 citations in OpenAlex.
- Serum estradiol to testosterone ratio as a novel predictor of severe preeclampsia in the first trimester.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Choroidal and retinal thickening in severe preeclampsia.Investigative ophthalmology & visual science · 2014Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of this study is to investigate whether preeclampsia is associated with exacerbation of insulin resistance. MATERIALS AND
methodsThe study was conducted over a period of 7 months from November 2011 to May 2012, in a tertiary care hospital attached to a medical college. A total of 14 pregnant women in the third trimester with preeclampsia were recruited for this study and 14 well-matched normotensive women in the third trimester were taken as control. 15 g, 50% dextrose load was given intravenously and blood sampling was carried out for glucose and insulin levels up to 3 h afterward. Minimal model analysis of glucose and insulin levels was performed to arrive at results.
resultsNo significant changes in mean age, body mass index, gestation, serum lipid and progesterone, cortisol and androgen concentrations were recognized. No significant difference was found between the glucose decay curves and between the glucose clearance rate K, in the two groups (preeclamptic vs. normotensive: 2.1 ± 0.2 vs. 2.2 ± 0.3; P = 0.48). Therefore, there was a small but prolonged decrease in the insulin response of women with preeclampsia compared with women in the normotensive group.
conclusionPreeclampsia per se is not a risk factor for development of insulin resistance.
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