ReviewWorld journal of gastrointestinal surgery2014
Prediction and diagnosis of colorectal anastomotic leakage: A systematic review of literature.
Review in World journal of gastrointestinal surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical and Economical Evaluation of Colorectal Surgery in Ambulatory Care
Comparison of the Effect of Chewing Gum and Honey on Postoperative Recovery and Complications in Ileostomy Reversal
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.
- Gut microbiota and postoperative complications in colorectal surgery and its potential association with intestinal permeability and NLRP6 inflammasome.Frontiers in immunology · 2025Pooled it
- Early complication detection after colorectal surgery (CONDOR): study protocol for a prospective clinical diagnostic study.International journal of colorectal disease · 2016Trial
- Integrated intraoperative strategies to prevent anastomotic leakage after laparoscopic low anterior resection: The roles of left colic artery preservation, reinforcement suturing, and transanal tube placement.The Journal of international medical research · 2026Article
- Trend of C-Reactive protein after colorectal surgery may increase predictive value of anastomotic leak: a prospective analysis.BMC surgery · 2026Article
- Endoscopic negative pressure therapy as a salvage treatment for management of post-surgical anastomotic leaks without ostomy after colorectal resection.Scientific reports · 2025Article
- Diagnostic value of CT scan findings for anastomotic leakage after low anterior resection without ileostomy in rectal cancer.Scientific reports · 2025Article
- Utility of C-reactive protein on the fourth postoperative day to detect complications beyond anastomotic dehiscence.International journal of colorectal disease · 2025Observational
- Bedside endoscopic inspection of colorectal anastomoses in the early postoperative period: a 2-center prospective feasibility study.Annals of coloproctology · 2025Article
- Early warning model to detect anastomotic leakage following colon surgery: a clinical observational study.Annals of coloproctology · 2024Article
- The Value of C-Reactive Protein and Peritoneal Cytokines as Early Predictors of Anastomotic Leak after Colorectal Surgery.Diagnostics (Basel, Switzerland) · 2024Article
- Article
- Efficacy of air leak test in detection of anastomotic leaks after rectal excision: a retrospective case-controlled study.Annals of surgical treatment and research · 2023Article
- Is ICG essential in all colorectal surgery? A 3-year experience in a single center: a cohort study.International journal of colorectal disease · 2023Article
- Predictive Factors for Anastomotic Leakage Following Colorectal Cancer Surgery: Where Are We and Where Are We Going?Current oncology (Toronto, Ont.) · 2023Review
- International survey among surgeons on the perioperative management of rectal cancer.Surgical endoscopy · 2023Article
- Role of Damage-Associated Molecular Patterns (DAMPS) in the Postoperative Period after Colorectal Surgery.International journal of molecular sciences · 2023Review
- Techniques for Diagnosing Anastomotic Leaks Intraoperatively in Colorectal Surgeries: A Review.Cureus · 2023Review
- MRI diagnose post-operative anastomotic leak in patients with rectal cancer: preliminary experience.BMC surgery · 2022Article
- The importance of inflammatory markers in detection of complications in patients with gastric cancer undergoing the Enhanced Recovery After Surgery (ERAS) protocol: a prospective cohort study.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022Article
- Serial assessment of inflammatory parameters for prediction of septic complications following surgery for colorectal endometriosis : A descriptive, retrospective study.Wiener klinische Wochenschrift · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although many studies have focused on the preoperative risk factors of anastomotic leakage after colorectal surgery (CAL), postoperative delay in diagnosis is common and harmful. This review provides a systematic overview of all available literature on diagnostic tools used for CAL. A systematic search of literature was undertaken using Medline, Embase, Cochrane and Web-of-Science libraries. Articles were selected when a diagnostic or prediction tool for CAL was described and tested. Two reviewers separately assessed the eligibility and level of evidence of the papers. Sixty-nine articles were selected (clinical methods: 11, laboratory tests: 12, drain fluid analysis: 12, intraoperative techniques: 22, radiology: 16). Clinical scoring leads to early awareness of probability of CAL and reduces delay of diagnosis. C-reactive protein measurement at postoperative day 3-4 is helpful. CAL patients are characterized by elevated cytokine levels in drain fluid in the very early postoperative phase in CAL patients. Intraoperative testing using the air leak test allows intraoperative repair of the anastomosis. Routine contrast enema is not recommended. If CAL is clinically suspected, rectal contrast-computer tomography is recommended by a few studies. In many studies a "no-test" control group was lacking, furthermore no golden standard for CAL is available. These two factors contributed to a relatively low level of evidence in the majority of the papers. This paper provides a systematic overview of literature on the available tools for diagnosing CAL. The study shows that colorectal surgery patients could benefit from some diagnostic interventions that can easily be performed in daily postoperative care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.