Evidence map›Paper›PMID 24600477›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2014

Manual khalifa therapy improves functional and morphological outcome of patients with anterior cruciate ligament rupture in the knee: a randomized controlled trial.

Michael Ofner, Andreas Kastner, Engelbert Wallenboeck, Robert Pehn, Frank Schneider, Reinhard Groell, Dieter Szolar, Harald Walach, Gerhard Litscher, Andreas Sandner-Kiesling

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. RegentK and Physiotherapy-Electrodermal Mapping.Medicines (Basel, Switzerland) · 2014
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michael OfnerDepartment of Sports and Exercise Physiology, University of Vienna, Auf der Schmelz 6, 1150 Vienna, Austria.ORCID 0000-0003-0964-0955
Andreas KastnerDepartment of Traumatology, General Hospital Linz, 4020 Linz, Austria.
Engelbert WallenboeckHospital of Traumatology, 8020 Graz, Austria.
Robert PehnDepartment of Traumatology, General Hospital Kirchdorf, 4560 Kirchdorf, Austria.
Frank SchneiderDepartment of Pediatric Orthopedics, Medical University of Graz, 8036 Graz, Austria.
Reinhard GroellInstitute of Radiology, Medical University of Graz, 8043 Graz, Austria.
Dieter SzolarInstitute of Radiology "Graz South-East", 8054 Graz, Austria.
Harald WalachInstitute of Transcultural Health Studies, European University Viadrina, 15207 Frankfurt Oder, Germany.
Gerhard LitscherStronach Research Unit for Complementary and Integrative Laser Medicine, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, and TCM Research Center Graz, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0001-6287-0130
Andreas Sandner-KieslingDepartment of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, 8036 Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rupture of the anterior cruciate ligament (ACL) is a high incidence injury usually treated surgically. According to common knowledge, it does not heal spontaneously, although some claim the opposite. Regeneration therapy by Khalifa was developed for injuries of the musculoskeletal system by using specific pressure to the skin. This randomized, controlled, observer-blinded, multicentre study was performed to validate this assumption. Thirty patients with complete ACL rupture, magnetic resonance imaging (MRI) verified, were included. Study examinations (e.g., international knee documentation committee (IKDC) score) were performed at inclusion (t 0). Patients were randomized to receive either standardised physiotherapy (ST) or additionally 1 hour of Khalifa therapy at the first session (STK). Twenty-four hours later, study examinations were performed again (t 1). Three months later control MRI and follow-up examinations were performed (t 2). Initial status was comparable between both groups. There was a highly significant difference of mean IKDC score results at t 1 and t 2. After 3 months, 47% of the STK patients, but no ST patient, demonstrated an end-to-end homogeneous ACL in MRI. Clinical and physical examinations were significantly different in t 1 and t 2. ACL healing can be improved with manual therapy. Physical activity can be performed without pain and nearly normal range of motion after one treatment of specific pressure.

Identifiers

PMID24600477
PMCPMC3926243

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.