ArticleFrontiers in human neuroscience2014
Probing the neurochemical basis of synaesthesia using psychophysics.
Article in Frontiers in human neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Synesthesia does not help to recover perceptual dominance following flash suppression.Scientific reports · 2021Article
- Assessing Lateral Interaction in the Synesthetic Visual Brain.Vision (Basel, Switzerland) · 2019Article
- General Anesthetic Conditions Induce Network Synchrony and Disrupt Sensory Processing in the Cortex.Frontiers in cellular neuroscience · 2016Article
- Phosphene Perception Relates to Visual Cortex Glutamate Levels and Covaries with Atypical Visuospatial Awareness.Cerebral cortex (New York, N.Y. : 1991) · 2015Article
- Color synesthesia. Insight into perception, emotion, and consciousness.Current opinion in neurology · 2015Review
- Developing synaesthesia: a primer.Frontiers in human neuroscience · 2015Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neurochemical mechanisms that contribute to synaesthesia are poorly understood, but multiple models implicate serotonin and GABA in the development of this condition. Here we used psychophysical tasks to test the predictions that synaesthetes would display behavioral performance consistent with reduced GABA and elevated serotonin in primary visual cortex. Controls and synaesthetes completed the orientation-specific surround suppression (OSSS) and tilt-after effect (TAE) tasks, previously shown to relate to GABA and serotonin levels, respectively. Controls and synaesthetes did not differ in the performance parameter previously associated with GABA or in the magnitude of the TAE. However, synaesthetes did display lower contrast difference thresholds in the OSSS task than controls when no surround (NS) was present. These results are inconsistent with the hypothesized roles of GABA and serotonin in this condition, but provide preliminary evidence that synaesthetes exhibit enhanced contrast discrimination.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.