ArticleClinical, cosmetic and investigational dermatology2014
An integral topical gel for cellulite reduction: results from a double-blind, randomized, placebo-controlled evaluation of efficacy.
Article in Clinical, cosmetic and investigational dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Phytochemistry and Wound-Healing, Enzyme-Inhibitory, and Antifungal Activities of the Wild Forage LegumePlants (Basel, Switzerland) · 2026Article
- Clinical Effectiveness of a Novel Caffeine Nano-Cream for Cellulite Reduction: A Randomised Double-Blind Trial.Pharmaceutics · 2026Article
- Review
- Effects of repeated use of a commercial topical lotion on subcutaneous fat thickness in resistance-trained male athletes.Journal of cosmetic dermatology · 2023Article
- Cellulite: Current Understanding and Treatment.Aesthetic surgery journal. Open forum · 2023Review
- Efficacy of an Anti-Cellulite Herbal Emgel: A Randomized Clinical Trial.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Insights Into the Pathophysiology of Cellulite: A Review.Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2020Review
- Beneficial role and function of fisetin in skin health via regulation of the CCN2/TGF-β signaling pathway.Food science and biotechnology · 2016Article
- Cellulite Reduction by Modified Thai Herbal Compresses; A Randomized Double-Blind Trial.Journal of evidence-based integrative medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCellulite is a serious cosmetic concern for most of the 90% of women affected by it.
objectiveTo assess the clinical efficacy of a complex integral anti-cellulite gel.
methodsThis double-blind, randomized, placebo-controlled study involved 44 healthy women, aged 25-55 years. Subjects had a normal to slightly overweight body mass index and presented slight to moderate cellulite on their thighs, buttocks, and/or hips at baseline. Subjects were randomly assigned to either the treated or placebo group and accordingly applied the active product or placebo on their hips, stomach, buttocks, and thighs, twice daily for 3 months. Skin tonicity, orange-peel aspect, and stubborn cellulite were assessed at day 0, 28, 56, and 84. A self-evaluation questionnaire was completed by all volunteers.
resultsAt the end of the study, an average of 81% of the subjects applying the active product presented improvement in their cellulite condition versus 32% for the placebo group (all descriptors and sites combined). At day 84, skin tonicity, orange-peel appearance, and stubborn cellulite were improved in a significant manner (P<0.05) over placebo, on all studied areas. Skin tonicity improved on average by +41% for buttocks, +35% for hips, and +31% for thighs. Orange peel appearance was reduced on average by -25% for buttocks, -22% for hips, and -22% for thighs. Stubborn cellulite was reduced on average by -19% for buttocks, -24% for hips, and -22% for thighs. Circumference measurements decreased in a significant manner (P<0.05) over placebo, for the abdomen (average value of -1.1 cm) and thighs (average value of -0.8 cm). The product was well tolerated and perceived by the volunteers themselves as better performing than placebo on all criteria.
conclusionAll results validate the efficacy of the present integral formulation to significantly reduce signs of cellulite and reshape the silhouette.
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