ReviewMicrobiology and molecular biology reviews : MMBR2014
Bacterial genome instability.
Review in Microbiology and molecular biology reviews : MMBR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 207 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
207 citing papers in PubMed, 401 citations in OpenAlex.
- Hypervirulence-associated pseudo-compound transposons as fundamental mobile units driving cross-species virulence dissemination in Enterobacteriaceae.PLoS pathogens · 2026Article
- Isolation, Identification, and Biological Characterization ofMicroorganisms · 2026Article
- Horizontal Gene Transfer and Genome Rearrangements Shape Bacterial Adaptation for Bioremediation.Environmental microbiology · 2026Review
- Adaptive evolution resulted in three subtypes of theJournal of bacteriology · 2026Article
- Microbial biobanking: safeguarding the tiny treasures for sustainable human welfare.Folia microbiologica · 2026Review
- A developmental condensin I complex assists the Paramecium PiggyMac domesticated transposase during programmed DNA elimination.Nucleic acids research · 2026Article
- Unlocking genome engineering inMicrobiology spectrum · 2026Article
- Genomic and proteomic analyses of the maize root isolateApplied and environmental microbiology · 2026Article
- Prevalence and Evolutionary Implications of Genome Rearrangements in Bacteria.Genome biology and evolution · 2026Article
- Plasmid mutation rates scale with copy number.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Termination of DNA replication drives genomic instability via multiple mechanisms.Nucleic acids research · 2026Article
- Accelerated Genomic Evolution and Divergence ofMicroorganisms · 2026Article
- Independent, ongoing clade-specific expansions of ISMicrobial genomics · 2026Article
- Evolutionary dynamics of type VI secretion systems in fruit fly-associatedFrontiers in microbiology · 2026Article
- Epidemiological trends of antibiotic resistance in pathogenic Escherichia coli in swine farms from the Northwest Iberian Peninsula and evaluation of air sampling for antibiotic resistance surveillance.Porcine health management · 2025Article
- De novo origin of numerous microproteins in enterobacteria.Nucleic acids research · 2025Article
- Conflicts between the DNA replication and repair machineries promote cell death in Gram-positive bacteria.Microbiology (Reading, England) · 2025Article
- Aerococcus christensenii: an emerging pathogen associated with infections and bacteremia in pregnancy-genomic insights and pathogenicity evaluation.Functional & integrative genomics · 2025Article
- Gene conversion and duplication contribute to genetic variation in an outbreak ofMicrobial genomics · 2025Article
- Hallmarks of Bacterial Vaginosis.Diagnostics (Basel, Switzerland) · 2025Review
147 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Bacterial genomes are remarkably stable from one generation to the next but are plastic on an evolutionary time scale, substantially shaped by horizontal gene transfer, genome rearrangement, and the activities of mobile DNA elements. This implies the existence of a delicate balance between the maintenance of genome stability and the tolerance of genome instability. In this review, we describe the specialized genetic elements and the endogenous processes that contribute to genome instability. We then discuss the consequences of genome instability at the physiological level, where cells have harnessed instability to mediate phase and antigenic variation, and at the evolutionary level, where horizontal gene transfer has played an important role. Indeed, this ability to share DNA sequences has played a major part in the evolution of life on Earth. The evolutionary plasticity of bacterial genomes, coupled with the vast numbers of bacteria on the planet, substantially limits our ability to control disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.