ReviewChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2014
Avian sex, sex chromosomes, and dosage compensation in the age of genomics.
Review in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 70 citations in OpenAlex.
- Transcriptomics Reveal Molecular Signatures of a Resolved Sexual Conflict and Potential Association With Colour Polymorphism in Tawny Owls.Molecular ecology · 2026Article
- Sharks and rays have the oldest vertebrate sex chromosome with unique sex determination mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Chromosome-level reference genome assembly of the gyrfalcon (Falco rusticolus) and population genomics offer insights into the falcon population in Mongolia.Scientific reports · 2025Article
- DNA Methylation Associates With Sex-Specific Effects of Experimentally Increased Yolk Testosterone in Wild Nestlings.Molecular ecology · 2025Article
- Review
- Review
- Dosage compensation of Z sex chromosome genes in avian fibroblast cells.Genome biology · 2023Article
- Recurrent chromosome reshuffling and the evolution of neo-sex chromosomes in parrots.Nature communications · 2022Article
- Polymorphism of Sex Determination Amongst Wild Populations Suggests its Rapid Turnover Within the Nile Tilapia Species.Frontiers in genetics · 2022Article
- Models and Molecular Markers of Spermatogonial Stem Cells in Vertebrates: To Find Models in Nonmammals.Stem cells international · 2022Review
- Article
- Genetic Regulation of Avian Testis Development.Genes · 2021Review
- Multiple sex chromosomes in teleost fishes from a cytogenetic perspective: state of the art and future challenges.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- The rates of introgression and barriers to genetic exchange between hybridizing species: sex chromosomes vs autosomes.Genetics · 2021Article
- Differences in Homomorphic Sex Chromosomes Are Associated with Population Divergence in Sex Determination inCells · 2021Article
- Sequence Transpositions Restore Genes on the Highly Degenerated W Chromosomes of Songbirds.Genes · 2020Article
- Evolutionary Dynamics of Sex Chromosomes of Paleognathous Birds.Genome biology and evolution · 2019Article
- Sex-Biased Gene Expression and Dosage Compensation on the Artemia franciscana Z-Chromosome.Genome biology and evolution · 2019Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Comparisons of the sex chromosome systems in birds and mammals are widening our view and deepening our understanding of vertebrate sex chromosome organization, function, and evolution. Birds have a very conserved ZW system of sex determination in which males have two copies of a large, gene-rich Z chromosome, and females have a single Z and a female-specific W chromosome. The avian ZW system is quite the reverse of the well-studied mammalian XY chromosome system, and evolved independently from different autosomal blocs. Despite the different gene content of mammal and bird sex chromosomes, there are many parallels. Genes on the bird Z and the mammal X have both undergone selection for male-advantage functions, and there has been amplification of male-advantage genes and accumulation of LINEs. The bird W and mammal Y have both undergone extensive degradation, but some birds retain early stages and some mammals terminal stages of the process, suggesting that the process is more advanced in mammals. Different sex-determining genes, DMRT1 and SRY, define the ZW and XY systems, but DMRT1 is involved in downstream events in mammals. Birds show strong cell autonomous specification of somatic sex differences in ZZ and ZW tissue, but there is growing evidence for direct X chromosome effects on sexual phenotype in mammals. Dosage compensation in birds appears to be phenotypically and molecularly quite different from X inactivation, being partial and gene-specific, but both systems use tools from the same molecular toolbox and there are some signs that galliform birds represent an early stage in the evolution of a coordinated system.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.