Trial reportThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Transcranial direct current stimulation over right dorsolateral prefrontal cortex enhances error awareness in older age.
Trial report in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The effect of the interval-between-sessions on prefrontal transcranial direct current stimulation (tDCS) on cognitive outcomes: a systematic review and meta-analysis.Journal of neural transmission (Vienna, Austria : 1996) · 2016Pooled it
- Effects of noninvasive brain stimulation on cognitive function in healthy aging and Alzheimer's disease: a systematic review and meta-analysis.Neurobiology of aging · 2015Pooled it
- Potential Delayed Positive Effects of tDCS on Improving Introspective Accuracy in Social Cognition in Schizophrenia.Schizophrenia bulletin · 2025Trial
- Evidence against benefits from cognitive training and transcranial direct current stimulation in healthy older adults.Nature human behaviour · 2021Trial
- Balanced bifrontal transcranial direct current stimulation enhances working memory in adults with high-functioning autism: a sham-controlled crossover study.Molecular autism · 2017Trial
- Transcranial Stimulation of the Dorsolateral Prefrontal Cortex Prevents Stress-Induced Working Memory Deficits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Trial
- Feasibility of using high-definition transcranial direct current stimulation (HD-tDCS) to enhance treatment outcomes in persons with aphasia.NeuroRehabilitation · 2015Trial
- Trial
- Tolerability of Repeated Application of Transcranial Electrical Stimulation with Limited Outputs to Healthy Subjects.Brain stimulationTrial
- Characterizing the behavioural correlates of error awareness with the novel speeded inference task.Scientific reports · 2026Article
- Article
- Noninvasive Therapies: A Forthcoming Approach to Parkinson's Treatment.CNS & neurological disorders drug targets · 2025Review
- Error monitoring under working memory load: An electrocortical investigation.Psychophysiology · 2024Article
- Neural and Behavioral Measures of Stress-induced Impairment in Error Awareness and Post-error Adjustment.Neuroscience bulletin · 2024Article
- Right-lateralized sleep spindles are associated with neutral over emotional bias in picture recognition: An overnight study.Cognitive, affective & behavioral neuroscience · 2023Article
- Does Executive Function Training Impact on Communication? A Randomized Controlled tDCS Study on Post-Stroke Aphasia.Brain sciences · 2022Article
- Prefrontal cortical activation associated with prospective memory while walking around a real-world street environment.NeuroImage · 2022Article
- Anodal and cathodal transcranial direct current stimulations of prefrontal cortex in a rodent model of Alzheimer's disease.Frontiers in aging neuroscience · 2022Article
- Transcranial Direct Current Stimulation of the Dorsolateral Prefrontal Cortex Modulates Cognitive Function Related to Motor Execution During Sequential Task: A Randomized Control Study.Frontiers in human neuroscience · 2022Article
- Non-invasive brain stimulation and neuroenhancement.Clinical neurophysiology practice · 2022Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability to detect errors during cognitive performance is compromised in older age and in a range of clinical populations. This study was designed to assess the effects of transcranial direct current stimulation (tDCS) on error awareness in healthy older human adults. tDCS was applied over DLPFC while subjects performed a computerized test of error awareness. The influence of current polarity (anodal vs cathodal) and electrode location (left vs right hemisphere) was tested in a series of separate single-blind, Sham-controlled crossover trials, each including 24 healthy older adults (age 65-86 years). Anodal tDCS over right DLPFC was associated with a significant increase in the proportion of performance errors that were consciously detected, and this result was recapitulated in a separate replication experiment. No such improvements were observed when the homologous contralateral area was stimulated. The present study provides novel evidence for a causal role of right DLPFC regions in subserving error awareness and marks an important step toward developing tDCS as a tool for remediating the performance-monitoring deficits that afflict a broad range of populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.