ArticlePediatric nephrology (Berlin, Germany)2014
Kidney size and function in a multi-ethnic population-based cohort of school-age children.
Article in Pediatric nephrology (Berlin, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Effect of Protein Intake Early in Life on Kidney Volume and Blood Pressure at 11 Years of Age.Nutrients · 2023Trial
- Maternal and fetal determinants on kidney size in early childhood: insights from a New York City cohort.BMC nephrology · 2026Article
- Kidney volume measurement and predictive modeling in children aged 0-18 years using a computer-assisted surgery system.Scientific reports · 2025Article
- Cystatin C as a Marker of Kidney Function in Children.Biomolecules · 2024Review
- Role of foetal kidney size on kidney function in childhood: the born in bradford cohort renal study.BMC nephrology · 2023Article
- Ultrasonographic reference values and a simple yet practical formula for estimating average kidney length in Japanese children.Clinical and experimental nephrology · 2022Article
- Impact of early-life diet on long-term renal health.Molecular and cellular pediatrics · 2020Review
- Kidney volume, kidney function, and ambulatory blood pressure in children born extremely preterm with and without nephrocalcinosis.Pediatric nephrology (Berlin, Germany) · 2019Article
- Renal size and cardiovascular risk in prepubertal children.Scientific reports · 2019Article
- Kidney volume and ambulatory blood pressure in children.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- Fetal first trimester growth is not associated with kidney outcomes in childhood.Pediatric nephrology (Berlin, Germany) · 2017Article
- Childhood Estimates of Glomerular Filtration Rate Based on Creatinine and Cystatin C: Importance of Body Composition.American journal of nephrology · 2017Article
- Assessment of kidney function in preterm infants: lifelong implications.Pediatric nephrology (Berlin, Germany) · 2016Review
- Influence of common genetic variants on childhood kidney outcomes.Pediatric research · 2016Article
- Protein intake in infancy and kidney size and function at the age of 6 years: The Generation R Study.Pediatric nephrology (Berlin, Germany) · 2015Article
- The Generation R Study: Biobank update 2015.European journal of epidemiology · 2014Article
- Comment on Sonographic Portal Vein Biometry in Apparently Healthy Children in Northeastern Nigeria.Journal of medical ultrasoundArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSubclinical impaired kidney growth and function in childhood may lead to kidney diseases and high blood pressure in adulthood. We assessed the cross-sectional associations of childhood characteristics with kidney size and function in a multi-ethnic cohort.
methodsThis study was embedded in a population-based cohort study of 6,397 children with a median age of 6.0 years.Kidney volume, creatinine and cystatin C blood levels, microalbuminuria and blood pressure were measured, and glomerular filtration rate (GFR) was estimated.
resultsChildhood anthropometrics were positively associated with kidney volume, creatinine level and blood pressure (all p < 0.05). We observed ethnic differences in all kidney size and function measures (all p < 0.05). Children with smaller kidneys had higher creatinine and cystatin C blood levels, leading to a lower estimated GFR [difference 5.68 ml/min/1.73 m2 (95% confidence interval 5.14-6.12) per 1 standard deviation increase in kidney volume]. Larger kidney volume was associated with an increased risk of microalbuminuria.
conclusionsChildhood kidney volume and function are influenced by body mass index and ethnicity. Kidney volume is related with kidney function but not with blood pressure. These results may help to identify individuals at risk for kidney disease in an early stage.
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