ArticleClinical research in cardiology : official journal of the German Cardiac Society2014
Effect of gender differences on 1-year mortality after transcatheter aortic valve implantation for severe aortic stenosis: results from a multicenter real-world registry.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Influence of Gender on Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2023Pooled it
- Impact of left ventricular conduction defect with or without need for permanent right ventricular pacing on functional and clinical recovery after TAVR.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Trial
- Long-Term Impact of Gender Differences After Transcatheter Aortic Valve Implantation.CJC open · 2024Article
- Female Sex and Low Flow: A Double Paradox in Aortic Stenosis?JACC. Advances · 2024Article
- Postoperative delirium in 47 379 individuals undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2023Review
- Does Gender Influence the Indication of Treatment and Long-Term Prognosis in Severe Aortic Stenosis?Journal of cardiovascular development and disease · 2023Article
- Sex difference and outcome trends following transcatheter aortic valve replacement.Frontiers in cardiovascular medicine · 2022Article
- Gender difference in left atrial appendage occlusion outcomes: Results from the Amplatzer™ Amulet™ Observational Study.International journal of cardiology. Heart & vasculature · 2021Article
- Sex difference in the prognostic role of body composition parameters in Taiwanese patients undergoing transcatheter aortic valve implantation.BMC cardiovascular disorders · 2020Observational
- Comparison of transthoracic and transesophageal echocardiography for transcatheter aortic valve replacement sizing in high-risk patients.Journal of echocardiography · 2020Article
- Gender-dependent association of diabetes mellitus with mortality in patients undergoing transcatheter aortic valve replacement.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Observational
- Favorable outcomes for female patients undergoing transcatheter aortic valve replacement?Annals of translational medicine · 2017Article
- Sex-related differences in clinical outcomes and quality of life after transcatheter aortic valve implantation for severe aortic stenosis.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2017Article
- The impact of transcatheter aortic valve implantation on quality of life: results from the German transcatheter aortic valve interventions registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
- Hotline update of clinical trials and registries presented at the American College of Cardiology Congress 2014.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Article
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this analysis is to examine the influence of gender differences on the outcome after transcatheter aortic valve implantation (TAVI) from a multicenter real-world registry in Germany (TAVI registry).
backgroundThe impact of gender differences on the clinical outcome after TAVI was examined in small studies with conflicting results.
methodsConsecutive patients (n = 1,432) undergoing TAVI in the period between January 2009 and June 2010 in Germany were evaluated. Differences in all-cause mortality were examined with Kaplan-Meier estimates and proportional hazards models.
resultsWomen comprised 57.8 % of the cohort. The Edwards Sapien valve (18.5 %) and CoreValve (81.5 %) were used through the transfemoral (87.7 %), subclavian (3.0 %), transapical (8.6 %), or transaortic approach (0.7 %). At baseline, women had higher aortic gradients and were older. Men had more comorbidities: prior myocardial infarction, prior revascularization, prior coronary artery bypass surgery, peripheral arterial vascular disease and chronic obstructive pulmonary disease. Women had more periprocedural vascular complications in comparison to men (25.2 vs. 17.2 %, p < 0.001). There was no significant difference in mortality at 30-day follow-up (7.6 % for women vs. 8.6 % for men, p = 0.55). The adjusted HR for 1-year all-cause mortality favored women, HR 0.75 (95 % CI 0.57-0.98, p = 0.0346) with a mortality rate of 17.3 vs. 23.6 % for men.
conclusionsFemale gender is associated with better 1-year survival after TAVI. These results suggest that TAVI could be the best treatment modality for elderly women with symptomatic severe aortic stenosis.
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