ArticleeLife2014
Dual mode of embryonic development is highlighted by expression and function of Nasonia pair-rule genes.
Article in eLife, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 69 citations in OpenAlex.
- Embryogenesis in Myrmicine Ants Combines Features of Short Germ-Band Development With a Progressive Mode of Segmentation.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025Article
- Genome-wide quantitative dissection of an arthropod segmented body plan at single-cell resolution.Communications biology · 2025Article
- Recent approaches lead to a deeper understanding of diverse segmentation mechanisms in insects, with a focus on the pair-rule genes.Current opinion in insect science · 2025Review
- The development and evolution of arthropod tagmata.Proceedings. Biological sciences · 2025Review
- Same rule, different genes:Science advances · 2024Article
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- Anterior-posterior patterning of segments in Anopheles stephensi offers insights into the transition from sequential to simultaneous segmentation in holometabolous insects.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2023Article
- The Nasonia pair-rule gene regulatory network retains its function over 300 million years of evolution.Development (Cambridge, England) · 2022Article
- Patterning with clocks and genetic cascades: Segmentation and regionalization of vertebrate versus insect body plans.PLoS genetics · 2021Review
- Time and space in segmentation.Interface focus · 2021Article
- smiFISH and embryo segmentation for single-cell multi-gene RNA quantification in arthropods.Communications biology · 2021Article
- Spatiotemporal variation in cell proliferation patterns during arthropod axial elongation.Scientific reports · 2021Article
- Regulatory gene function handoff allows essential gene loss in mosquitoes.Communications biology · 2020Article
- The embryonic expression pattern of a second, hitherto unrecognized, paralog of the pair-rule gene sloppy-paired in the beetle Tribolium castaneum.Development genes and evolution · 2020Article
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- TheBiology open · 2019Article
- Shifting roles ofDevelopment (Cambridge, England) · 2019Article
- The mlpt/Ubr3/Svb module comprises an ancient developmental switch for embryonic patterning.eLife · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Embryonic anterior-posterior patterning is well understood in Drosophila, which uses 'long germ' embryogenesis, in which all segments are patterned before cellularization. In contrast, most insects use 'short germ' embryogenesis, wherein only head and thorax are patterned in a syncytial environment while the remainder of the embryo is generated after cellularization. We use the wasp Nasonia (Nv) to address how the transition from short to long germ embryogenesis occurred. Maternal and gap gene expression in Nasonia suggest long germ embryogenesis. However, the Nasonia pair-rule genes even-skipped, odd-skipped, runt and hairy are all expressed as early blastoderm pair-rule stripes and late-forming posterior stripes. Knockdown of Nv eve, odd or h causes loss of alternate segments at the anterior and complete loss of abdominal segments. We propose that Nasonia uses a mixed mode of segmentation wherein pair-rule genes pattern the embryo in a manner resembling Drosophila at the anterior and ancestral Tribolium at the posterior. DOI: http://dx.doi.org/10.7554/eLife.01440.001.
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