ArticleThe ISME journal2014
Molecular epidemiology and population structure of the honey bee brood pathogen Melissococcus plutonius.
Article in The ISME journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Evaluating efficacy of oxytetracycline, lincomycin, and tylosin for treatment of clinical European foulbrood disease.Journal of insect science (Online) · 2026Article
- Potential confounding factors in currently used antibiotic susceptibility assays for the honey bee pathogenJournal of medical microbiology · 2025Article
- Antimicrobial control and temporal dynamics of M. plutonius colonization in adult worker honey bees (Apis mellifera).PloS one · 2025Article
- Article
- Quantitative tyramine analysis method for Apis mellifera larvae infected with Melissococcus plutonius, the causative agent of European foulbrood.The Journal of veterinary medical science · 2024Article
- Bacterial communities associated with Acrobeles complexus nematodes recovered from tomato crops in South Africa.PloS one · 2024Article
- Identification of peptides from honeybee gut symbionts as potential antimicrobial agents against Melissococcus plutonius.Nature communications · 2023Article
- Atypical Melissococcus plutonius strains: their characteristics, virulence, epidemiology, and mysteries.The Journal of veterinary medical science · 2023Review
- Caffeine Consumption Helps Honey Bees Fight a Bacterial Pathogen.Microbiology spectrum · 2023Article
- Population genetic diversity and dynamics of the honey bee brood pathogen Melissococcus plutonius in a region with high prevalence.Journal of invertebrate pathology · 2023Article
- A high-throughput sequencing survey characterizing European foulbrood disease and Varroosis in honey bees.Scientific reports · 2023Article
- Investigation ofThe Canadian veterinary journal = La revue veterinaire canadienne · 2022Article
- Molecular Detection and Differentiation of Arthropod, Fungal, Protozoan, Bacterial and Viral Pathogens of Honeybees.Veterinary sciences · 2022Review
- A novel multiplex PCR assay to detect and distinguish between different types of Paenibacillus larvae and Melissococcus plutonius, and a survey of foulbrood pathogen contamination in Japanese honey.The Journal of veterinary medical science · 2022Article
- Bacterial communities associated with Zeldia punctata, a bacterivorous soil-borne nematode.International microbiology : the official journal of the Spanish Society for Microbiology · 2022Article
- Identifying the climatic drivers of honey bee disease in England and Wales.Scientific reports · 2021Article
- Validation of Diagnostic Methods for European Foulbrood on Commercial Honey Bee Colonies in the United States.Journal of insect science (Online) · 2021Article
- Pathogens Spillover from Honey Bees to Other Arthropods.Pathogens (Basel, Switzerland) · 2021Review
- Peritrophic matrix-degrading proteins are dispensable virulence factors in a virulent Melissococcus plutonius strain.Scientific reports · 2021Article
- Putative determinants of virulence inVirulence · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Melissococcus plutonius is the causative agent of European foulbrood (EFB), which is a serious brood disease of the European honey bee (Apis mellifera). EFB remains a threat because of a poor understanding of disease epidemiology. We used a recently published multi-locus sequence typing method to characterise 206 M. plutonius isolates recovered from outbreaks in England and Wales over the course of 2 years. We detected 15 different sequence types (STs), which were resolved by eBURST and phylogenetic analysis into three clonal complexes (CCs) 3, 12 and 13. Single and double locus variants within CC3 were the most abundant and widespread genotypes, accounting for 85% of the cases. In contrast, CCs 12 and 13 were rarer and predominantly found in geographical regions of high sampling intensity, consistent with a more recent introduction and localised spread. K-function analysis and interpoint distance tests revealed significant geographical clustering in five common STs, but pointed to different dispersal patterns between STs. We noted that CCs appeared to vary in pathogenicity and that infection caused by the more pathogenic variants is more likely to lead to honey bee colony destruction, as opposed to treatment. The importance of these findings for improving our understanding of disease aetiology and control are discussed.
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