ReviewMedicine and science in sports and exercise2014
Heat waves, aging, and human cardiovascular health.
Review in Medicine and science in sports and exercise, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
118 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Meta-analysis of heat-induced changes in cardiac function from over 400 laboratory-based heat exposure studies.Nature communications · 2025Pooled it
- Pooled it
- Global Health Impacts for Economic Models of Climate Change: A Systematic Review and Meta-Analysis.Annals of the American Thoracic Society · 2022Pooled it
- The direct and urinary electrolyte-mediated effects of ambient temperature on population blood pressure: A causal mediation analysis.Environment international · 2025Trial
- Identifying the Optimal Heat Exposure Metric for Predicting the Physiological Response to Dry or Humid Heat Stress in Young and Older Adults: A Randomized Controlled Study.Environmental health perspectives · 2024Trial
- Age differences in cardiac autonomic regulation during intermittent exercise in the heat.European journal of applied physiology · 2020Trial
- Age Modulates Physiological Responses during Fan Use under Extreme Heat and Humidity.Medicine and science in sports and exercise · 2017Trial
- Trial
- Impairments in central cardiovascular function contribute to attenuated reflex vasodilation in aged skin.Journal of applied physiology (Bethesda, Md. : 1985) · 2015Trial
- Cognitive and perceptual responses during passive heat stress in younger and older adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2015Trial
- Study Protocol for the Daasanach Human Biology Project: A Longitudinal Study of the Impact of Drinking Water Salinity and Heat Stress on Water Insecurity, Hydration, Energetics, Hypertension, and Kidney Function in Northern Kenya.American journal of human biology : the official journal of the Human Biology Council · 2026Article
- The Effect of Nighttime Heatwave on Poststroke Disability in Subtropical Cities of China.Environment & health (Washington, D.C.) · 2026Article
- Epidemiology, mechanisms and clinical implications of heat-related kidney disease.Nature reviews. Nephrology · 2026Review
- Identifying heat-related diagnoses in emergency department visits among adults in Chicago: A heat-wide association study.Science advances · 2026Article
- The association between heat waves and pregnancy outcome among women undergoing assisted reproductive technology in Sichuan, China.BMC public health · 2026Article
- Intersection of Climate and Environmental Change and Priority Health Outcomes Across the Life Course: Working Group 1 Report from the "Agriculture and Diet: Value Added for Nutrition, Translation, and Adaptation in a Global Ecology" (ADVANTAGE) Project.Advances in nutrition (Bethesda, Md.) · 2026Review
- Cause-specific heat-related mortality in Rio de Janeiro city: Comparing exposure metrics and the role of exposure duration.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Development and external validation of a machine learning-based Cox model for predicting in-hospital survival in classic heatstroke: a multicenter retrospective study.Scientific reports · 2026Article
- Four-Days of Passive Heat Acclimation Increases Exercise Capacity in Healthy Older Adults Living in the UK.Healthcare (Basel, Switzerland) · 2026Article
- Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
This brief review is based on a President's Lecture presented at the Annual Meeting of the American College of Sports Medicine in 2013. The purpose of this review was to assess the effects of climate change and consequent increases in environmental heat stress on the aging cardiovascular system. The earth's average global temperature is slowly but consistently increasing, and along with mean temperature changes come increases in heat wave frequency and severity. Extreme passive thermal stress resulting from prolonged elevations in ambient temperature and prolonged physical activity in hot environments creates a high demand on the left ventricle to pump blood to the skin to dissipate heat. Even healthy aging is accompanied by altered cardiovascular function, which limits the extent to which older individuals can maintain stroke volume, increase cardiac output, and increase skin blood flow when exposed to environmental extremes. In the elderly, the increased cardiovascular demand during heat waves is often fatal because of increased strain on an already compromised left ventricle. Not surprisingly, excess deaths during heat waves 1) occur predominantly in older individuals and 2) are overwhelmingly cardiovascular in origin. Increasing frequency and severity of heat waves coupled with a rapidly growing at-risk population dramatically increase the extent of future untoward health outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.