ArticleThe Plant journal : for cell and molecular biology2014
Recognition of floral homeotic MADS domain transcription factors by a phytoplasmal effector, phyllogen, induces phyllody.
Article in The Plant journal : for cell and molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed.
- Phytoplasma-plant interactions: effector-mediated host reprogramming, hormonal crosstalk, metabolic alterations and plant-mediated vector manipulation.World journal of microbiology & biotechnology · 2026Review
- Potato purple top phytoplasma infection induces autophagy-associated lipid dynamics that support pathogen proliferation.Plant physiology · 2026Article
- The pathogenic effector PHYL1The Plant journal : for cell and molecular biology · 2026Article
- Putative Effector Genes Reveal Hidden Genetic Diversity Beyond Conventional Typing Markers in Flavescence Dorée Phytoplasmas.Pathogens (Basel, Switzerland) · 2026Article
- The phytoplasma effector, phyllogen, structurally mimics host plant MADS transcription factors.The Journal of biological chemistry · 2026Article
- Comparative genomics of a poinsettia-associated phytoplasma and functional validation of its SAP11-homologous effectors that induce plant branching.Microbial genomics · 2026Article
- Extended phenotype of phytoplasmas in eukaryotic systems: mechanisms and ecological implications.Frontiers in plant science · 2026Review
- Effector innovation in genome-reduced phytoplasmas and other host-dependent mollicutes.PLoS genetics · 2025Article
- Dasineura asteriae Reprograms the Flower Gene Expressions of Vegetative Organs to Create Flower-Like Gall in Aster scaber.Plant, cell & environment · 2025Article
- Dual RNA-seq reveals the global transcriptome ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Status and Distribution of Diseases Caused by Phytoplasmas in Africa.Microorganisms · 2025Review
- Sequencing and comparative analyses of 'Microbial genomics · 2025Article
- Comprehensive genomic and functional characterization of a phytoplasma associated with root retardation, early bolting, witches'-broom, and phyllody in daikon (Frontiers in microbiology · 2025Article
- 'Pathogens (Basel, Switzerland) · 2024Article
- Definition of the effector landscape across 13 phytoplasma proteomes with LEAPH and EffectorComb.NAR genomics and bioinformatics · 2024Article
- A phytoplasma effector destabilizes chloroplastic glutamine synthetase inducing chlorotic leaves that attract leafhopper vectors.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Structural insights into the molecular mechanism of phytoplasma immunodominant membrane protein.IUCrJ · 2024Article
- Phytoplasma: A plant pathogen that cannot be ignored in agricultural production-Research progress and outlook.Molecular plant pathology · 2024Review
- Target degradation specificity of phytoplasma effector phyllogen is regulated by the recruitment of host proteasome shuttle protein.Molecular plant pathology · 2024Article
- Detection, Identification and Molecular Characterization of the 16SrII-V Subgroup Phytoplasma Strain Associated withPlants (Basel, Switzerland) · 2023Article
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12 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Plant pathogens alter the course of plant developmental processes, resulting in abnormal morphology in infected host plants. Phytoplasmas are unique plant-pathogenic bacteria that transform plant floral organs into leaf-like structures and cause the emergence of secondary flowers. These distinctive symptoms have attracted considerable interest for many years. Here, we revealed the molecular mechanisms of the floral symptoms by focusing on a phytoplasma-secreted protein, PHYL1, which induces morphological changes in flowers that are similar to those seen in phytoplasma-infected plants. PHYL1 is a homolog of the phytoplasmal effector SAP54 that also alters floral development. Using yeast two-hybrid and in planta transient co-expression assays, we found that PHYL1 interacts with and degrades the floral homeotic MADS domain proteins SEPALLATA3 (SEP3), APETALA1 (AP1) and CAULIFLOWER (CAL). This degradation of MADS domain proteins was dependent on the ubiquitin-proteasome pathway. The expression of floral development genes downstream of SEP3 and AP1 was disrupted in 35S::PHYL1 transgenic plants. PHYL1 was genetically and functionally conserved among other phytoplasma strains and species. We designate PHYL1, SAP54 and their homologs as members of the phyllody-inducing gene family of 'phyllogens'.
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