Evidence map›Paper›PMID 24596700›Full record

ArticleMuscles, ligaments and tendons journal2013

Strength and muscle mass loss with aging process. Age and strength loss.

Karsten Keller, Martin Engelhardt

3 registry-linked trialsAbstract read
PubMed Full text at PMC
In one paragraph

Article in Muscles, ligaments and tendons journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 240 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
240citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03737890 nacompletednot on this mapstarted 2018, after this paper: background citation

Comparison of Hold Relax Pectoral Stretch & Inspiratory Muscle Training on Pulmonary Function Among Frail Elderly

TypeinterventionalSponsorUniversiti Tunku Abdul RahmanRan2018 to 2020Enrolled30ConditionsPulmonary Function in Frail ElderlyArmsInspiratory Muscle Training, Hold Relax Pectoral Stretch
NCT07362329 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Use of Resistive Exercise Snacks to Improve Upper Body Fitness in Graduate Students

TypeinterventionalSponsorNew York Institute of TechnologyRan2026 to 2026Enrolled50ConditionsMuscle Strength, Muscle Power, Physical EnduranceArmsSubmaximal Repeated Exercise Snack, Maximal One-Time Exercise Snack
NCT07624370 enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Impatto Della Diagnosi di fragilità Sulla tossicità da Terapia in Pazienti Anziani Affetti da Tumore oncoLogIco e onCoEmatologico.

TypeobservationalSponsorAzienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di LegnanoRan2025 to 2028Enrolled160ConditionsSarcopenia in Elderly, Frailty/Sarcopenia, Oncological Patients, Hematologic DiseaseArmsFrailty evaluation
3 · Its place in the literature

Who cites it

240 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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180 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Karsten KellerCentrum Thrombosis and Haemostasis, University Medical Center Mainz of Johannes Gutenberg-University Mainz, Mainz, Germany ; Department of Medicine 2, University Medical Center Mainz of Johannes Gutenberg-University Mainz, Mainz, Germany.
Martin EngelhardtDepartment for orthopedics, trauma surgery and hand surgery, Klinikum Osnabrück, Osnabrück, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundaging process is associated with changes in muscle mass and strength with decline of muscle strength after the 30(th) life year. The aim of this study was to investigate these changes in muscle mass and strength. PATIENTS &

methodsfor this analysis 26 participants were subdivided in two groups. Group 1 comprises participants aged <40 years (n=14), group 2 those >40 years (n=12). We assessed anthropometrics, range of motions, leg circumferences and isometric strength values of the knee joints.

resultsbesides comparable anthropometrics, circumferences and strength were higher in group 1 than in group 2. Circumference of upper leg (20 cm above knee articular space) showed for right leg a trend to a significant (median: 54.45 cm (1(st) quartile: 49.35/3(rd) quartile: 57.78) vs 49.80 cm (49.50/50.75), p=0.0526) and for left leg a significant 54.30 cm (49.28/58.13) vs 49.50 cm (48.00/52.53), p=0.0356) larger circumference in group 1. Isometric strength was in 60° knee flexion significantly higher in group 1 than in group 2 for right (729.88N (561.47/862.13) vs 456.92N (304.67/560.12), p=0.00448) and left leg (702.49N (581.36/983.87) vs 528.49N (332.95/648.58), p=0.0234).

conclusionsaging process leads to distinct muscle mass and strength loss. Muscle strength declines from people aged <40 years to those >40 years between 16.6% and 40.9%.

Indexed as

ageagingisometricmusclesarcopeniastrength

Identifiers

PMID24596700
PMCPMC3940510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.