ArticleHead and neck pathology2014
Neuroendocrine neoplasms of the head and neck: some suggestions for the new WHO classification of head and neck tumors.
Article in Head and neck pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 53 citations in OpenAlex.
- Neuroendocrine tumor G1 in sphenoid sinuses: A case report.Radiology case reports · 2025Article
- Middle ear neuroendocrine tumor with multiple brain metastases: a case report and literature review.Frontiers in oncology · 2024Review
- Primary Small Cell Neuroendocrine Carcinoma of nasopharynx with metastatic cervical lymph nodes: an exceedingly rare entity with review of literature.BMJ case reports · 2023Review
- Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumours: Tumours of the Ear.Head and neck pathology · 2022Article
- Poorly differentiated carcinoma with neuroendocrine features in two patients with sinonasal tumours: a report of two cases.The Pan African medical journal · 2022Article
- Malignant Sinonasal Tumors: Update on Histological and Clinical Management.Current oncology (Toronto, Ont.) · 2021Review
- Primary carcinoid tumor in the external auditory canal.Journal of pathology and translational medicine · 2020Article
- A Rare Case of Locally Advanced Recurrent Neuroendocrine Tumour of Neck Salvaged by a Radical Surgical Approach.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019Article
- Article
- Primary small cell carcinoma of the larynx. Survival time of 47 months. Case report.Annals of medicine and surgery (2012) · 2018Article
- Role of ancillary techniques in profiling unclassified laryngeal malignancies.Virchows Archiv : an international journal of pathology · 2018Review
- Successful cisplatin-etoposide chemotherapy-based treatment of a primary small cell neuroendocrine carcinoma of the tonsil with multiple metastases: a case report.OncoTargets and therapy · 2018Article
- Recurrent Adenomatous Neuroendocrine Tumor of the Middle Ear: A Diagnostic Challenge.Case reports in otolaryngology · 2018Article
- Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Preface.Head and neck pathology · 2017Article
- Sinonasal Carcinomas with Neuroendocrine Features: Histopathological Differentiation and Treatment Outcomes.Journal of neurological surgery. Part B, Skull base · 2016Article
- Should patients with laryngeal small cell neuroendocrine carcinoma receive prophylactic cranial irradiation?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016Review
- Large Cell Neuroendocrine Carcinoma of the Head and Neck: A Clinicopathologic Series of 10 Cases With an Emphasis on HPV Status.The American journal of surgical pathology · 2016Article
- Neuroendocrine Neoplasms of the Sinonasal Tract: Neuroendocrine Carcinomas and Olfactory Neuroblastoma.Head and neck pathology · 2016Review
- A Rare Primary Neuroendocrine Tumor (Typical Carcinoid) of the Sublingual Gland.Case reports in dentistry · 2016Article
- Large cell neuroendocrine carcinoma of the head and neck: a distinct clinicopathologic entity.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2014Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
As knowledge and understanding in pathology evolve, classifications and nomenclature also change to reflect those advances. The 2005 World Health Organization Classification of Head and Neck Tumours was a significant step towards diagnostic standardization of head and neck neuroendocrine carcinomas; however, in the last 10 years there have been new data supporting the recognition of "large cell neuroendocrine carcinoma" as a distinctive high grade carcinoma in the head and neck, a lesion not included in the 2005 Classification. In addition, the terms "middle ear adenoma" and "carcinoid tumor of middle ear" are still widely used to describe a neoplasm that is neither a pure adenoma nor a carcinoid tumor but a lesion with variable mixed exocrine and endocrine differentiation. Largely using the diagnostic criteria of the WHO classification of neuroendocrine carcinomas of the lung, we propose the terms "neuroendocrine carcinoma, grade 1"; "neuroendocrine carcinoma, grade 2"; "neuroendocrine carcinoma, grade 3, large cell type"; and "neuroendocrine carcinoma, grade 3, small cell type" for the classification of neuroendocrine carcinomas of the head and neck in a future WHO classification. In addition, we also proposed the term "mixed epithelial neuroendocrine tumor" of the middle ear as an alternative for "middle ear adenoma" and "carcinoid tumor of the middle ear".
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