ArticleMolecules (Basel, Switzerland)2014
Astragalus membranaceus improves exercise performance and ameliorates exercise-induced fatigue in trained mice.
Article in Molecules (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Trial
- Astragalosides Supplementation Enhances Intrinsic Muscle Repair Capacity Following Eccentric Exercise-Induced Injury.Nutrients · 2022Trial
- Standardized astragalus extract for attenuation of the immunosuppression induced by strenuous physical exercise: randomized controlled trial.Journal of the International Society of Sports Nutrition · 2021Trial
- Repressed Exercise-Induced Hepcidin Levels after Danggui Buxue Tang Supplementation in Male Recreational Runners.Nutrients · 2018Trial
- Effects of Chinese Medicine as Adjunct Medication for Adjuvant Chemotherapy Treatments of Non-Small Cell Lung Cancer Patients.Scientific reports · 2017Trial
- Effects of YuPingFeng granules on acute exacerbations of COPD: a randomized, placebo-controlled study.International journal of chronic obstructive pulmonary diseaseTrial
- Elucidating the mechanisms underlying differential anthocyanin biosynthesis and its link to stem color and root isoflavonoid levels inHorticulture research · 2026Article
- Cycloastragenol improves tolerance to acute hypoxic exhaustive exercise stress in mice: integrated network pharmacology and experimental evidence.Frontiers in nutrition · 2026Article
- Study on the Anti-fatigue Effects of Polysaccharides from Erjing Formula.Current pharmaceutical biotechnology · 2026Article
- Herbal extract (Integrative medicine research · 2024Article
- Exploring the complex immunomodulatory effects and gut defense via oral administration of Astragali radix water extract to normal mice.BMC complementary medicine and therapies · 2024Article
- Synergistic Integration of Traditional Chinese Medicine and Western Medical Intervention in the Treatment of Brain Abscess: A Case Report.The Yale journal of biology and medicine · 2024Article
- Effects of ChlorichFoods (Basel, Switzerland) · 2024Article
- A standardized herbal combination ofFrontiers in nutrition · 2024Article
- Anti-fatigue effect of traditional Chinese medicines: A review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Review
- Acupoint Catgut Embedding Improves Lipid Metabolism in Exercise-Induced Fatigue Rats via the PPAR Signaling Pathway.Animals : an open access journal from MDPI · 2023Article
- Efficacy and safety of Qixue Tongzhi Granule in improving the exercise capacity of stable coronary artery disease: study protocol for a multicenter, randomized, double-blind, placebo-controlled trial.Frontiers in cardiovascular medicine · 2023Article
- Effects of salidroside on exercise tolerance of mice under high altitude hypoxia environment.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022Article
- Highly Efficient Biotransformation of Notoginsenoside R1 into Ginsenoside Rg1 byJournal of microbiology and biotechnology · 2022Article
- Article
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6 authors.
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Abstract
Astragalus membranaceus (AM) is a popular "Qi-tonifying" herb with a long history of use as a Traditional Chinese Medicine with multiple biological functions. However, evidence for the effects of AM on exercise performance and physical fatigue is limited. We evaluated the potential beneficial effects of AM on ergogenic and anti-fatigue functions following physiological challenge. Male ICR strain mice were randomly assigned to four groups (n = 10 per group) for treatment: (1) sedentary control and vehicle treatment (vehicle control); (2) exercise training with vehicle treatment (exercise control); and (3) exercise training with AM treatment at 0.615 g/kg/day (Ex-AM1) or (4) 3.075 g/kg/day (Ex-AM5). Both the vehicle and AM were orally administered for 6 weeks. Exercise performance and anti-fatigue function were evaluated by forelimb grip strength, exhaustive swimming time, and levels of serum lactate, ammonia, glucose, and creatine kinase after 15-min swimming exercise. Exercise training combined with AM supplementation increased endurance exercise capacity and increased hepatic and muscle glycogen content. AM reduced exercise-induced accumulation of the byproducts blood lactate and ammonia with acute exercise challenge. Moreover, we found no deleterious effects from AM treatment. Therefore, AM supplementation improved exercise performance and had anti-fatigue effects in mice. It may be an effective ergogenic aid in exercise training.
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